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Literature summary for 1.2.1.5 extracted from

  • Stagos, D.; Chen, Y.; Cantore, M.; Jester, J.V.; Vasiliou, V.
    Corneal aldehyde dehydrogenases: multiple functions and novel nuclear localization (2010), Brain Res. Bull., 81, 211-218.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.1.5

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus isoform ALDH3A1 Mus musculus 5634
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-hydroxy-2-nonenal + NAD(P)+ + H2O Mus musculus
-
 ? + NAD(P)H + H+
-
 ?
malondialdehyde + NAD(P)+ + H2O Mus musculus
-
 ? + NAD(P)H + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q9JHW9
-
-

Source Tissue

Source Tissue Comment Organism Textmining
corneal epithelium isoform ALDH3A1 Mus musculus
-
keratocyte
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-hydroxy-2-nonenal + NAD(P)+ + H2O
-
 Mus musculus ? + NAD(P)H + H+
-
 ?
malondialdehyde + NAD(P)+ + H2O
-
 Mus musculus ? + NAD(P)H + H+
-
 ?

Subunits

Subunits Comment Organism
homodimer isoform ALDH3A1 Mus musculus

Synonyms

Synonyms Comment Organism
ALDH3A1
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Mus musculus
NADP+
-
 Mus musculus

General Information

General Information Comment Organism
physiological function isoforms ALDH3A1 plays a protective role against ultraviolet radiation-induced oxidative damage to ocular tissues, detoxifies reactive aldehydes and acts as antioxidant Mus musculus