KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.4 | - |
NADP+ | - |
Ovis aries | |
1.2 | - |
2-keto-3-deoxy-D-glucose | - |
Ovis aries |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-keto-3-deoxy-D-glucose + NADP+ + H2O | Rattus norvegicus | - |
2-keto-3-deoxy-D-gluconic acid + NADPH + H+ | - |
? | |
2-keto-3-deoxy-D-glucose + NADP+ + H2O | Ovis aries | - |
2-keto-3-deoxy-D-gluconic acid + NADPH + H+ | - |
? | |
methylglyoxal + NADP+ + H2O | Rattus norvegicus | - |
pyruvate + NADPH + H+ | - |
? | |
methylglyoxal + NADP+ + H2O | Ovis aries | - |
pyruvate + NADPH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ovis aries | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
using treatment with acetone, ammonium sulfate fractionation, and gel filtration on Sephadex G-25 | Ovis aries |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
liver | - |
Ovis aries | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-keto-3-deoxy-D-glucose + NADP+ + H2O | - |
Rattus norvegicus | 2-keto-3-deoxy-D-gluconic acid + NADPH + H+ | - |
? | |
2-keto-3-deoxy-D-glucose + NADP+ + H2O | - |
Ovis aries | 2-keto-3-deoxy-D-gluconic acid + NADPH + H+ | - |
? | |
2-keto-3-deoxy-D-glucose + NADP+ + H2O | - |
Ovis aries | 2-keto-3-deoxy-D-gluconate + NADPH + H+ | - |
r | |
2-oxoaldehydes + NADP+ + H2O | enzyme from sheep or rat liver also active with NAD+, see also EC 1.2.1.23 | Rattus norvegicus | 2-oxo acids + NADPH | - |
? | |
2-oxoaldehydes + NADP+ + H2O | enzyme from sheep or rat liver also active with NAD+, see also EC 1.2.1.23 | Ovis aries | 2-oxo acids + NADPH | - |
? | |
methylglyoxal + NADP+ + H2O | - |
Rattus norvegicus | pyruvate + NADPH + H+ | - |
? | |
methylglyoxal + NADP+ + H2O | - |
Ovis aries | pyruvate + NADPH + H+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | enzyme from sheep or rat liver, see also EC 1.2.1.23 | Rattus norvegicus | |
NAD+ | enzyme from sheep or rat liver, see also EC 1.2.1.23 | Ovis aries | |
NADP+ | - |
Rattus norvegicus | |
NADP+ | - |
Ovis aries |