Literature summary for 1.2.1.46 extracted from

Zhang, J.; Yue, X.; Luo, H.; Jiang, W.; Mei, Y.; Ai, L.; Gao, G.; Wu, Y.; Yang, H.; An, J.; Ding, S.; Yang, X.; Sun, B.; Luo, W.; He, R.; Jia, J.; Lyu, J.; Tong, Z.
Illumination with 630-nm red light reduces oxidative stress and restores memory by photo-activating catalase and formaldehyde dehydrogenase in SAMP8 mice (2019), Antioxid. Redox Signal., 30, 1432-1449 .

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Inhibitors

Inhibitors	Comment	Organism	Structure
H2O2	-	Homo sapiens
H2O2	-	Mus musculus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	contains zinc	Mus musculus
Zn2+	contains zinc	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
formaldehyde + NAD+ + H2O	Mus musculus	-	formate + NADH + 2 H+	-	?
formaldehyde + NAD+ + H2O	Homo sapiens	-	formate + NADH + 2 H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Mus musculus	-	senescence-accelerated prone 8 mouse model of age-related dementia	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Mus musculus	-
Neuro-2a cell	-	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
formaldehyde + NAD+ + H2O	-	Mus musculus	formate + NADH + 2 H+	-	?
formaldehyde + NAD+ + H2O	-	Homo sapiens	formate + NADH + 2 H+	-	?

Subunits

Subunits	Comment	Organism
?	x * 40000, SDS-PAGE	Mus musculus
?	x * 40000, SDS-PAGE	Homo sapiens

Synonyms

Synonyms	Comment	Organism
ADH3	-	Mus musculus
ADH3	-	Homo sapiens
FDH	-	Mus musculus
FDH	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Mus musculus
NAD+	-	Homo sapiens

Expression

Organism	Comment	Expression
Mus musculus	illumination with 630 nm red light from a light-emitting diode markedly activates the enzyme	up
Homo sapiens	illumination with 630 nm red light from a light-emitting diode markedly activates the enzyme	up

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Release 2023.1 (January 2023)