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Literature summary for 1.2.1.24 extracted from

  • Ferrer, E.; Cooper, R.A.
    a single succinic semialdehyde dehydrogenase is involved in 4-hydroxyphenylacetate and 4-aminobutyrate catabolism in Klebsiella pneumoniae M5a1 (1988), FEMS Microbiol. Lett., 52, 161-164.
No PubMed abstract available

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
52000
-
gel filtration Klebsiella pneumoniae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
succinate semialdehyde + NAD+ + H2O Klebsiella pneumoniae enzyme is induced by succinate semialdehyde, functions in the oxidation of succinate semialdehyde during growth on both 4-hydroxyphenylacetate and 4-aminobutyrate succinate + NADH
-
?
succinate semialdehyde + NAD+ + H2O Klebsiella pneumoniae M5a1 enzyme is induced by succinate semialdehyde, functions in the oxidation of succinate semialdehyde during growth on both 4-hydroxyphenylacetate and 4-aminobutyrate succinate + NADH
-
?

Organism

Organism UniProt Comment Textmining
Klebsiella pneumoniae
-
M5a1
-
Klebsiella pneumoniae M5a1
-
M5a1
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
succinate semialdehyde + NAD+ + H2O
-
Klebsiella pneumoniae succinate + NADH
-
?
succinate semialdehyde + NAD+ + H2O enzyme is induced by succinate semialdehyde, functions in the oxidation of succinate semialdehyde during growth on both 4-hydroxyphenylacetate and 4-aminobutyrate Klebsiella pneumoniae succinate + NADH
-
?
succinate semialdehyde + NAD+ + H2O
-
Klebsiella pneumoniae M5a1 succinate + NADH
-
?
succinate semialdehyde + NAD+ + H2O enzyme is induced by succinate semialdehyde, functions in the oxidation of succinate semialdehyde during growth on both 4-hydroxyphenylacetate and 4-aminobutyrate Klebsiella pneumoniae M5a1 succinate + NADH
-
?
succinate semialdehyde + NADP+ + H2O activity with NAD+ is 10times higher than with NADP+ Klebsiella pneumoniae succinate + NADPH
-
?
succinate semialdehyde + NADP+ + H2O activity with NAD+ is 10times higher than with NADP+ Klebsiella pneumoniae M5a1 succinate + NADPH
-
?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Klebsiella pneumoniae
NADP+ cofactor Klebsiella pneumoniae
NADP+ activity with NAD+ is 10times higher than with NADP+ Klebsiella pneumoniae