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Literature summary for 1.2.1.22 extracted from

  • MacCabe, A.; Sanmartin, G.; Orejas, M.
    Identification of the genes encoding the catalytic steps corresponding to LRA4 (l-2-keto-3-deoxyrhamnonate aldolase) and L-lactaldehyde dehydrogenase in Aspergillus nidulans evidence for involvement of the loci AN9425/lraD and AN0544/aldA in the L-rhamnose catabolic pathway (2021), Environ. Microbiol., 23, 2420-2432 .
    View publication on PubMed
Search for more literature for 1.2.1.22

Cloned(Commentary)

Cloned (Comment) Organism
gene AN0544 or aldA, DNA and amino acid sequence determination and analysis, genetic organization Aspergillus nidulans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-lactaldehyde + NAD+ + H2O Aspergillus nidulans
-
 (S)-lactate + NADH + 2 H+
-
 ?
(S)-lactaldehyde + NAD+ + H2O Aspergillus nidulans ATCC 38163
-
 (S)-lactate + NADH + 2 H+
-
 ?
(S)-lactaldehyde + NAD+ + H2O Aspergillus nidulans CBS 112.46
-
 (S)-lactate + NADH + 2 H+
-
 ?
(S)-lactaldehyde + NAD+ + H2O Aspergillus nidulans FGSC A4
-
 (S)-lactate + NADH + 2 H+
-
 ?
(S)-lactaldehyde + NAD+ + H2O Aspergillus nidulans M139
-
 (S)-lactate + NADH + 2 H+
-
 ?
(S)-lactaldehyde + NAD+ + H2O Aspergillus nidulans NRRL 194
-
 (S)-lactate + NADH + 2 H+
-
 ?

Organism

Organism UniProt Comment Textmining
Aspergillus nidulans Q5BFY6 Aspergillus nidulans
-
Aspergillus nidulans ATCC 38163 Q5BFY6 Aspergillus nidulans
-
Aspergillus nidulans CBS 112.46 Q5BFY6 Aspergillus nidulans
-
Aspergillus nidulans FGSC A4 Q5BFY6 Aspergillus nidulans
-
Aspergillus nidulans M139 Q5BFY6 Aspergillus nidulans
-
Aspergillus nidulans NRRL 194 Q5BFY6 Aspergillus nidulans
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-lactaldehyde + NAD+ + H2O
-
 Aspergillus nidulans (S)-lactate + NADH + 2 H+
-
 ?
(S)-lactaldehyde + NAD+ + H2O
-
 Aspergillus nidulans ATCC 38163 (S)-lactate + NADH + 2 H+
-
 ?
(S)-lactaldehyde + NAD+ + H2O
-
 Aspergillus nidulans CBS 112.46 (S)-lactate + NADH + 2 H+
-
 ?
(S)-lactaldehyde + NAD+ + H2O
-
 Aspergillus nidulans FGSC A4 (S)-lactate + NADH + 2 H+
-
 ?
(S)-lactaldehyde + NAD+ + H2O
-
 Aspergillus nidulans M139 (S)-lactate + NADH + 2 H+
-
 ?
(S)-lactaldehyde + NAD+ + H2O
-
 Aspergillus nidulans NRRL 194 (S)-lactate + NADH + 2 H+
-
 ?
acetaldehyde + NAD+
-
 Aspergillus nidulans acetate + NADH + H+
-
 ?
acetaldehyde + NAD+
-
 Aspergillus nidulans ATCC 38163 acetate + NADH + H+
-
 ?
acetaldehyde + NAD+
-
 Aspergillus nidulans CBS 112.46 acetate + NADH + H+
-
 ?
acetaldehyde + NAD+
-
 Aspergillus nidulans FGSC A4 acetate + NADH + H+
-
 ?
acetaldehyde + NAD+
-
 Aspergillus nidulans M139 acetate + NADH + H+
-
 ?
acetaldehyde + NAD+
-
 Aspergillus nidulans NRRL 194 acetate + NADH + H+
-
 ?

Synonyms

Synonyms Comment Organism
AldA
-
 Aspergillus nidulans
aldehyde dehyrogenase
-
 Aspergillus nidulans
AN0544
-
 Aspergillus nidulans
L-lactaldehyde dehydrogenase
-
 Aspergillus nidulans
LADH
-
 Aspergillus nidulans
More cf. EC 1.2.1.3 Aspergillus nidulans

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Aspergillus nidulans

General Information

General Information Comment Organism
metabolism the enzyme is involved in the non-phosphoryating L-rhamnose catabolic pathway Aspergillus nidulans