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Literature summary for 1.17.1.4 extracted from

  • You, S.; Zhu, B.; Wang, F.; Han, H.; Sun, M.; Zhu, H.; Peng, R.; Yao, Q.
    A Vitis vinifera xanthine dehydrogenase gene, VvXDH, enhances salinity tolerance in transgenic Arabidopsis (2017), Plant Biotechnol. Rep., 11, 147-160 .
No PubMed abstract available

Cloned(Commentary)

Cloned (Comment) Organism
gene VvXDH, sequence comparisons and phylogenetic analysis, synthesis of gene VvXDH through PCR-based two-step DNA synthesis method, recombinant overexpression in Arabidopsis thaliana ecotype Columbia under control of CaMV 35S promoter from plasmid pYM817 using the Agrobacterium tumefaciens strain GV3101 transfection method. The transgenic Arabidopsis thaliana plants show enhanced salt tolerance, phenotype, overview. Explicit function of VvXDH in conferring salt stress by increasing allantoin accumulation and activating abscisic acid signaling pathway, enhancing ROS scavenging in transgenic Arabidopsis thaliana. Expression of VvXDH results in elevated allantoin accumulation Vitis vinifera

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
xanthine + NAD+ + H2O Vitis vinifera
-
urate + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Vitis vinifera F6GU50
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
xanthine + NAD+ + H2O
-
Vitis vinifera urate + NADH + H+
-
?

Synonyms

Synonyms Comment Organism
VvXDH
-
Vitis vinifera
XDH
-
Vitis vinifera

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
assay at Vitis vinifera

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Vitis vinifera

General Information

General Information Comment Organism
physiological function xanthine dehydrogenase plays an important role in purine catabolism catalyzing the oxidative hydroxylation of hypoxanthine to xanthine and of xanthine to uric acid, it plays a role in recycling and remobilization of nitrogen, and XDH is implicated in plant stress responses and acclimation. Explicit function of VvXDH in conferring salt stress by increasing allantoin accumulation and activating abscisic acid signaling pathway, enhancing ROS scavenging in transgenic Arabidopsis thaliana. VvXDH application results in increased tolerance to abiotic stresses by elevating allantoin accumulation Vitis vinifera