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Literature summary for 1.17.1.4 extracted from

  • Stark, K.; Seubert, P.; Lynch, G.; Baudry, M.
    Proteolytic conversion of xanthine dehydrogenase to xanthine oxidase: Evidence against a role for calcium-activated protease (calpain) (1989), Biochem. Biophys. Res. Commun., 165, 858-864.
    View publication on PubMed
Search for more literature for 1.17.1.4

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
90000
-
 x * 140000, SDS-PAGE, trypsin-treated: x * 90000, SDS-PAGE, conversion of dehydrogenase to oxidase activity Rattus sp.
140000
-
 x * 140000, SDS-PAGE, trypsin-treated: x * 90000, SDS-PAGE, conversion of dehydrogenase to oxidase activity Rattus sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
xanthine + NAD+ + H2O Rattus sp. trypsin treatment leads to a complete conversion of xanthine dehydrogenase to xanthine oxidase activity urate + NADH
-
 r

Organism

Organism UniProt Comment Textmining
Rattus sp.
-
-
-

Purification (Commentary)

Purification (Comment) Organism
to homogeneity, chromatography techniques Rattus sp.

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus sp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
xanthine + NAD+ + H2O trypsin treatment leads to a complete conversion of xanthine dehydrogenase to xanthine oxidase activity Rattus sp. urate + NADH
-
 r

Subunits

Subunits Comment Organism
? x * 140000, SDS-PAGE, trypsin-treated: x * 90000, SDS-PAGE, conversion of dehydrogenase to oxidase activity Rattus sp.

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Rattus sp.
NADH
-
 Rattus sp.