Crystallization (Comment) | Organism |
---|---|
structure of CarC/Fe(II)/2-oxoglutarate complex | Pectobacterium carotovorum subsp. carotovorum |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | Fe(II)-dependent oxygenase. An Fe(IV)-oxo intermediate abstracts the hydrogen (H*) from C5, and tyrosine 165, a residue not visualized in the published structures of CarC lacking bound substrate, donates H* to the opposite face of the resultant radical. The reaction oxidizes the Fe(II) cofactor to Fe(III), limiting wild-type CarC to one turnover, but substitution of the H-donating tyrosine disables stereoinversion and confers to CarC the capacity for catalytic substrate oxidation | Pectobacterium carotovorum subsp. carotovorum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pectobacterium carotovorum subsp. carotovorum | Q9XB59 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
CarC | - |
Pectobacterium carotovorum subsp. carotovorum |