Cloned (Comment) | Organism |
---|---|
expression in Saccharomyces cerevisiae | Rattus norvegicus |
Protein Variants | Comment | Organism |
---|---|---|
A361Q | activity is significantly lower than that of wild-type enzyme | Rattus norvegicus |
DELTA238P/DELTA239L | activity is significantly lower than that of wild-type enzyme | Rattus norvegicus |
DELTA238P/DELTA239L | decreased or null DELTA6 desaturase activity | Rattus norvegicus |
F166V/V167L | activity is significantly lower than that of wild-type enzyme | Rattus norvegicus |
F356V/S358T | activity is significantly lower than that of wild-type enzyme | Rattus norvegicus |
H410Y/E413K | activity is significantly lower than that of wild-type enzyme | Rattus norvegicus |
I192T | activity is significantly lower than that of wild-type enzyme | Rattus norvegicus |
K234N/S235M/L236delta | decreased or null DELTA6 desaturase activity | Rattus norvegicus |
K234N/S235M/L236DELTA/K444Q | activity is significantly lower than that of wild-type enzyme | Rattus norvegicus |
K444Q | decreased or null DELTA6 desaturase activity | Rattus norvegicus |
N156T/A305V/Y182F/K234N/S235M/E365K/F166V/L423F/L424A/I195L/W245V | acquisition of DELTA5 desaturase activity without losing DELTA6 desaturase activity | Rattus norvegicus |
N156T/A305V/Y182F/K234N/S235M/E365K/F166V/L423F/L424A/L248V/F322L/L323F/I195L/W245V | acquisition of DELTA5 desaturase activity without losing DELTA6 desaturase activity | Rattus norvegicus |
N156T/A305V/Y182F/K234N/S235M/E365K/F166V/L423F/L424A/L248V/F322L/L323F/I195L/W245V/L396Y/V344P | acquisition of DELTA5 desaturase activity without losing DELTA6 desaturase activity | Rattus norvegicus |
N156T/A305V/Y182F/K234N/S235M/E365K/F166V/L423F/L424A/L248V/F322L/L323F/I195L/W245V/L396Y/Y257H | acquisition of DELTA5 desaturase activity without losing DELTA6 desaturase activity | Rattus norvegicus |
N156T/A305V/Y182F/K234N/S235M/E365K/F166V/L423F/L424A/L248V/F322L/L323F/I195L/W245V/L396Y/Y257H/V344P/I284F | acquisition of DELTA5 desaturase activity without losing DELTA6 desaturase activity | Rattus norvegicus |
N156T/A305V/Y182F/K234N/S235M/E365K/F166V/L423F/L424A/L248V/F322L/L323F/I195L/W245V/L396Y/Y257H/V344P/I284F/F370A/I326V | acquisition of DELTA5 desaturase activity without losing DELTA6 desaturase activity | Rattus norvegicus |
N156T/A305V/Y182F/K234N/S235M/E365K/F166V/L423F/L424A/L248V/F322L/L323F/I195L/W245V/L396Y/Y257H/V344P/I284F/F370A/Y352N | acquisition of DELTA5 desaturase activity without losing DELTA6 desaturase activity | Rattus norvegicus |
N156T/A305V/Y182F/K234N/S235M/E365K/F166V/L423F/L424A/L248V/F322L/L323F/I195L/W245V/L396Y/Y257H/V344P/I284F/F370A/Y352N/I326V/Y188F/K190T | acquisition of DELTA5 desaturase activity without losing DELTA6 desaturase activity | Rattus norvegicus |
N156T/A305V/Y182F/K234N/S235M/E365K/F166V/L423F/L424A/L248V/F322L/L323F/I195L/W245V/L396Y/Y257H/V344P/I284F/F370A/Y352N/I326V/Y188F/K190T/H410Y | acquisition of DELTA5 desaturase activity without losing DELTA6 desaturase activity | Rattus norvegicus |
N156T/A305V/Y182F/K234N/S235M/E365K/F166V/L423F/L424A/L248V/F322L/L323F/I195L/W245V/L396Y/Y257H/V344P/I284F/F370A/Y352N/I326V/Y188F/K190T/H410Y/E413K | acquisition of DELTA5 desaturase activity without losing DELTA6 desaturase activity | Rattus norvegicus |
N156T/A305V/Y182F/K234N/S235M/E365K/F166V/L423F/L424A/L248V/F322L/L323F/I195L/W245V/L396Y/Y257H/V344P/I284F/Y352N/I326V/H410Y | acquisition of DELTA5 desaturase activity without losing DELTA6 desaturase activity | Rattus norvegicus |
N156T/A305V/Y182F/K234N/S235M/E365K/F166V/L423F/L424A/L248V/F322L/L323F/W245V | acquisition of DELTA5 desaturase activity without losing DELTA6 desaturase activity | Rattus norvegicus |
P246S/L247V/Y249L | activity is significantly lower than that of wild-type enzyme | Rattus norvegicus |
Q415E/E416S | activity is significantly lower than that of wild-type enzyme | Rattus norvegicus |
Q415E/E416S | decreased or null DELTA6 desaturase activity | Rattus norvegicus |
R216M | activity is significantly lower than that of wild-type enzyme | Rattus norvegicus |
R216M | decreased or null DELTA6 desaturase activity | Rattus norvegicus |
S209P/N211S | activity is significantly lower than that of wild-type enzyme | Rattus norvegicus |
S209P/N211S | decreased or null DELTA6 desaturase activity | Rattus norvegicus |
Y352N/R353V | activity is significantly lower than that of wild-type enzyme | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | bound | Rattus norvegicus | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | Q9Z122 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
DELTA6 desaturase | - |
Rattus norvegicus |
FADS2 | - |
Rattus norvegicus |