Literature summary for 1.14.15.33 extracted from

Lee, S.K.; Park, J.W.; Kim, J.W.; Jung, W.S.; Park, S.R.; Choi, C.Y.; Kim, E.S.; Kim, B.S.; Ahn, J.S.; Sherman, D.H.; Yoon, Y.J.
Neopikromycin and novapikromycin from the pikromycin biosynthetic pathway of Streptomyces venezuelae (2006), J. Nat. Prod., 69, 847-849.

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Organism

Organism	UniProt	Comment	Textmining
Streptomyces venezuelae	O87605	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
10-deoxymethymycin + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2	i.e. YC-17	Streptomyces venezuelae	methymycin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O	-	?
10-deoxymethymycin + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2	-	Streptomyces venezuelae	neomethymycin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O	-	?
narbomycin + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2	-	Streptomyces venezuelae	neopikromycin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O	C14 hydroxylation product of narbomycin	?
narbomycin + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2	-	Streptomyces venezuelae	pikromycin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O	-	?
narbomycin + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2	-	Streptomyces venezuelae	novapikromycin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O	C12,C14-dihydroxylated product of narbomycin	?

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Release 2023.1 (January 2023)