Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Pseudomonas aeruginosa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
41600 | - |
- |
Pseudomonas aeruginosa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | Q9I1C2 | - |
- |
Pseudomonas aeruginosa DSM 22644 | Q9I1C2 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ethanesulfonate + FMNH2 + O2 | 27% of the activity with methanesulfonate | Pseudomonas aeruginosa | acetaldehyde + FMN + sulfite + H2O | - |
? | |
ethanesulfonate + FMNH2 + O2 | 27% of the activity with methanesulfonate | Pseudomonas aeruginosa DSM 22644 | acetaldehyde + FMN + sulfite + H2O | - |
? | |
isethionate + FMNH2 + O2 | 19% of the activity with methanesulfonate | Pseudomonas aeruginosa | hydroxyacetaldehyde + FMN + sulfite + H2O | - |
? | |
isethionate + FMNH2 + O2 | 19% of the activity with methanesulfonate | Pseudomonas aeruginosa DSM 22644 | hydroxyacetaldehyde + FMN + sulfite + H2O | - |
? | |
methanesulfonate + FMNH2 + O2 | - |
Pseudomonas aeruginosa | formaldehyde + FMN + sulfite + H2O | - |
? | |
methanesulfonate + FMNH2 + O2 | - |
Pseudomonas aeruginosa DSM 22644 | formaldehyde + FMN + sulfite + H2O | - |
? | |
morpholinepropanesulfonic acid + FMNH2 + O2 | 17% of the activity with methanesulfonate | Pseudomonas aeruginosa | 3-(morpholin-4-yl)propanal + FMN + sulfite + H2O | - |
? | |
morpholinepropanesulfonic acid + FMNH2 + O2 | 17% of the activity with methanesulfonate | Pseudomonas aeruginosa DSM 22644 | 3-(morpholin-4-yl)propanal + FMN + sulfite + H2O | - |
? | |
pentanesulfonate + FMNH2 + O2 | 13% of the activity with methanesulfonate | Pseudomonas aeruginosa | pentanal + FMN + sulfite + H2O | - |
? | |
pentanesulfonate + FMNH2 + O2 | 13% of the activity with methanesulfonate | Pseudomonas aeruginosa DSM 22644 | pentanal + FMN + sulfite + H2O | - |
? | |
piperazine-N,N'-bis(2-ethanesulfonic acid) + 2 FMNH2 + 2 O2 | 31% of the activity with methanesulfonate | Pseudomonas aeruginosa | 2,2'-piperazine-1,4-diyldiacetaldehyde + 2 FMN + 2 sulfite + 2 H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 41600, calculated | Pseudomonas aeruginosa |
Synonyms | Comment | Organism |
---|---|---|
msuD | - |
Pseudomonas aeruginosa |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Pseudomonas aeruginosa | calculated | - |
6.6 |
Organism | Comment | Expression |
---|---|---|
Pseudomonas aeruginosa | expression of the msu operon is repressed in the presence of sulfate, sulfite, sulfide, or cysteine | down |
Pseudomonas aeruginosa | growth with methanesulfonate requires an intact cysB gene, and the msu operon is part of the cys regulon | additional information |
Pseudomonas aeruginosa | expression of the msu operon is derepressed during growth with methionine or alkanesulfonates | up |
General Information | Comment | Organism |
---|---|---|
physiological function | the MsuD protein catalyzes the desulfonation of alkanesulfonates, requiring oxygen and FMNH2 for the reaction, and shows highest activity with methanesulfonate. NADH-dependent flavin mononucleotide reductase MsuE provides reduced FMN for the MsuD enzyme. Putative monooxygenase MsuC is involved but not essential in the desulfonation process | Pseudomonas aeruginosa |