Application | Comment | Organism |
---|---|---|
medicine | in the trophoblast choriocarcinoma cell line, JEG-3, the expression of let-7g microRNA is downregulated, but upregulated in primary term trophoblast. Aromatase is upregulated in JEG-3 cells but downregulated in primary trophoblast. Let-7g antagomirs and mimics increase and decrease aromatase expression, respectively, and Let-7g directly targets the 3'-untranslated region of CYP19A1 mRNAlet-7g antagomirs and mimics robustly increase and decrease production of estradiol, respectively | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P11511 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
JEG-3 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
CYP19A1 | - |
Homo sapiens |