Inhibitors | Comment | Organism | Structure |
---|---|---|---|
6-phospho-D-gluconate | substrate inhibition | Ctenopharyngodon idella | |
Al3+ | - |
Ctenopharyngodon idella | |
Cd2+ | competitive inhibition | Ctenopharyngodon idella | |
Cu2+ | competitive inhibition | Ctenopharyngodon idella | |
NADP+ | substrate inhibition | Ctenopharyngodon idella | |
NADPH | competitive inhibition | Ctenopharyngodon idella | |
Zn2+ | competitive inhibition | Ctenopharyngodon idella |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0052 | - |
NADP+ | at pH 8.0 and 25°C | Ctenopharyngodon idella | |
0.019 | - |
6-phospho-D-gluconate | at pH 8.0 and 25°C | Ctenopharyngodon idella |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
57000 | - |
2 * 57000, SDS-PAGE | Ctenopharyngodon idella |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
6-phospho-D-gluconate + NADP+ | Ctenopharyngodon idella | - |
D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ctenopharyngodon idella | - |
grass carp | - |
Purification (Comment) | Organism |
---|---|
2',5'-ADP-Sepharose 4B column chromatography | Ctenopharyngodon idella |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hepatopancreas | - |
Ctenopharyngodon idella | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.017 | - |
unpurified enzyme, at pH 8.0 and 25°C | Ctenopharyngodon idella |
5.259 | - |
after 309fold purification, at pH 8.0 and 25°C | Ctenopharyngodon idella |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
6-phospho-D-gluconate + NADP+ | - |
Ctenopharyngodon idella | D-ribulose 5-phosphate + CO2 + NADPH + H+ | - |
r |
Subunits | Comment | Organism |
---|---|---|
homodimer | 2 * 57000, SDS-PAGE | Ctenopharyngodon idella |
Synonyms | Comment | Organism |
---|---|---|
6-phosphogluconate dehydrogenase | - |
Ctenopharyngodon idella |
6PGD | - |
Ctenopharyngodon idella |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
50 | - |
- |
Ctenopharyngodon idella |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
- |
Ctenopharyngodon idella |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | dependent on | Ctenopharyngodon idella |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0285 | - |
Cd2+ | at pH 8.0 and 25°C | Ctenopharyngodon idella | |
0.032 | - |
NADPH | at pH 8.0 and 25°C | Ctenopharyngodon idella | |
0.084 | - |
Cu2+ | at pH 8.0 and 25°C | Ctenopharyngodon idella | |
0.12 | - |
NADP+ | at pH 8.0 and 25°C | Ctenopharyngodon idella | |
0.144 | - |
Zn2+ | at pH 8.0 and 25°C | Ctenopharyngodon idella | |
2.05 | - |
6-phospho-D-gluconate | at pH 8.0 and 25°C | Ctenopharyngodon idella |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.045 | - |
at pH 8.0 and 25°C | Ctenopharyngodon idella | Cd2+ | |
0.099 | - |
at pH 8.0 and 25°C | Ctenopharyngodon idella | Zn2+ | |
0.293 | - |
at pH 8.0 and 25°C | Ctenopharyngodon idella | Cu2+ | |
1.526 | - |
at pH 8.0 and 25°C | Ctenopharyngodon idella | Al3+ |