Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | - |
Amycolatopsis methanolica | |
CuCl2 | - |
Amycolatopsis methanolica | |
HgCl2 | - |
Amycolatopsis methanolica | |
KCN | - |
Amycolatopsis methanolica | |
additional information | inhibition differs for ethanol and formaldehyde as substrates | Amycolatopsis methanolica |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.2 | - |
1-Octanol | - |
Amycolatopsis methanolica | |
1.7 | - |
12-Hydroxydodecanoic acid | - |
Amycolatopsis methanolica | |
3.4 | - |
1-Hexanol | - |
Amycolatopsis methanolica | |
26.5 | - |
1-Pentanol | - |
Amycolatopsis methanolica | |
84 | - |
1-butanol | - |
Amycolatopsis methanolica | |
324 | - |
1-propanol | - |
Amycolatopsis methanolica | |
343 | - |
ethanol | - |
Amycolatopsis methanolica |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zinc | 6.1 atoms/enzyme molecule | Amycolatopsis methanolica |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
40000 | - |
3 * 40000, SDS-PAGE | Amycolatopsis methanolica |
117000 | 120000 | PAGE, gel filtration | Amycolatopsis methanolica |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
long-chain alcohol + NAD+ + H2O | Amycolatopsis methanolica | enzyme also uses formaldehyde and short chain aliphatic alcohols | long-chain carboxylate + NADH | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Amycolatopsis methanolica | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-octanol + 2 NAD+ + H2O | - |
Amycolatopsis methanolica | octanoic acid + 2 NADH + 2 H+ | - |
r | |
12-hydroxydodecanoic acid + NAD+ + H2O | - |
Amycolatopsis methanolica | ? + NADH | - |
? | |
ethanol + NAD+ + H2O | - |
Amycolatopsis methanolica | ethanal + NADH | - |
? | |
long-chain alcohol + NAD+ + H2O | enzyme also uses formaldehyde and short chain aliphatic alcohols | Amycolatopsis methanolica | long-chain carboxylate + NADH | - |
? | |
n-butanol + NAD+ + H2O | - |
Amycolatopsis methanolica | n-butanal + NADH | - |
? | |
n-hexanol + NAD+ + H2O | - |
Amycolatopsis methanolica | n-hexanal + NADH | - |
? | |
n-pentanol + NAD+ + H2O | - |
Amycolatopsis methanolica | n-pentanal + NADH | - |
? | |
n-propanol + NAD+ + H2O | - |
Amycolatopsis methanolica | n-propanal + NADH | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | N-terminal sequence | Amycolatopsis methanolica |
trimer | 3 * 40000, SDS-PAGE | Amycolatopsis methanolica |