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EC Tree
The expected taxonomic range for this enzyme is: Aspergillus
Reaction Schemes
ergosteryl-3beta-O-L-aspartate
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Synonyms
ErdH, ergosteryl-3beta-O-L-aspartate hydrolase,
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ergosteryl-3beta-O-L-aspartate hydrolase
ErdH
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ergosteryl-3beta-O-L-aspartate hydrolase
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ergosteryl-3beta-O-L-aspartate hydrolase
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ergosteryl-3beta-O-L-aspartate + H2O = ergosterol + L-aspartate
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ergosteryl-3beta-O-L-aspartate acylhydrolase
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ergosteryl-3beta-O-L-aspartate + H2O
ergosterol + L-aspartate
ergosteryl-3beta-O-L-aspartate + H2O
ergosterol + L-aspartate
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ergosteryl-3beta-O-L-aspartate + H2O
ergosterol + L-aspartate
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ergosteryl-3beta-O-L-aspartate + H2O
ergosterol + L-aspartate
ergosteryl-3beta-O-L-aspartate + H2O
ergosterol + L-aspartate
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ergosteryl-3beta-O-L-aspartate + H2O
ergosterol + L-aspartate
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physiological function
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ErdH is a ergosteryl-3beta-O-L-aspartate hydrolase participating in the turnover of the conjugated sterol in vivo
physiological function
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ErdH is a ergosteryl-3beta-O-L-aspartate hydrolase participating in the turnover of the conjugated sterol in vivo
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D277A
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mutation in predicted catalytic triad, inactive
H307A
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mutation in predicted catalytic triad, inactive
S153A
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mutation in predicted catalytic triad, inactive
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Yakobov, N.; Fischer, F.; Mahmoudi, N.; Saga, Y.; Grube, C.D.; Roy, H.; Senger, B.; Grob, G.; Tatematsu, S.; Yokokawa, D.; Mouyna, I.; Latge, J.-P.; Nakajima, H.; Kushiro, T.; Becker, H.D.
RNA-dependent sterol aspartylation in fungi
Proc. Natl. Acad. Sci. USA
117
14948-14957
2020
Aspergillus fumigatus, Aspergillus oryzae
brenda
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3.1.1.B13 ergosteryl-3beta-O-L-aspartate hydrolase
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