Disease on EC 2.3.1.28 - chloramphenicol O-acetyltransferase
Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Acidosis
Normoxic induction of cerebral HIF-1alpha by acetazolamide in rats: role of acidosis.
Adenocarcinoma
Murine pulmonary surfactant SP-A gene: cloning, sequence, and transcriptional activity.
Adenocarcinoma
Structure of human estrogen and aryl sulfotransferase gene. Two mRNA species issued from a single gene.
Adenocarcinoma
The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells.
Adenocarcinoma
Tumor-selective gene transduction and cell killing with an oncotropic autonomous parvovirus-based vector.
Adenocarcinoma
Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture.
Adenocarcinoma of Lung
Characterization of the promoter of human pulmonary surfactant protein B gene.
Adenocarcinoma of Lung
cis-acting elements involved in the regulation of mouse Clara cell-specific 10-kDa protein gene. In vitro and in vivo analysis.
Adenocarcinoma of Lung
Enhanced reporter gene expression in cells transfected in the presence of DMI-2, an acid nuclease inhibitor.
Adenocarcinoma of Lung
SP-A 3'-UTR is involved in the glucocorticoid inhibition of human SP-A gene expression.
Adenoviridae Infections
Adenovirus E1A represses the cyclic AMP-induced transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) in hepatoma cells.
Anemia
Localization of sequences responsible for trans-activation of the equine infectious anemia virus long terminal repeat.
Astrocytoma
Constitutive expression of human immunodeficiency virus (HIV) nef protein in human astrocytes does not influence basal or induced HIV long terminal repeat activity.
Astrocytoma
Effect of eukaryotic initiation factor 4F on AUG selection in a bicistronic mRNA.
Bacterial Infections
In vivo expression of the beta-glucoside (bgl) operon of Escherichia coli occurs in mouse liver.
Brain Ischemia
Diffuse cerebral ischemia in the cat: I. Local blood flow during severe ischemia and recirculation.
Brain Ischemia
Diffuse cerebral ischemia in the cat: II. Regional metabolites during severe ischemia and recirculation.
Brain Ischemia
Diffuse cerebral ischemia in the cat: III. Neuropathological sequelae of severe ischemia.
Breast Neoplasms
Bifunctional gonadotropin-releasing hormone antagonist-progesterone analogs with increased efficacy and duration of action.
Breast Neoplasms
Characterization of the chromosomal gene and promoter for human insulin-like growth factor binding protein-5.
Breast Neoplasms
Comparative estrogenic activity of wine extracts and organochlorine pesticide residues in food.
Breast Neoplasms
Differences in 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible CYP1A1 expression in human breast carcinoma cell lines involve altered trans-acting factors.
Breast Neoplasms
Establishment of in vitro test system for the evaluation of the estrogenic activities of natural products.
Breast Neoplasms
Estrogenic potential of progestins in oral contraceptives to stimulate human breast cancer cell proliferation.
Breast Neoplasms
Gene regulation studies of aromatase expression in breast cancer and adipose stromal cells.
Breast Neoplasms
Human P45IA1 upstream regulatory sequences expressing the chloramphenicol acetyltransferase gene. Effect of Ha-MSV enhancer and comparison of transient with stable transformation assays.
Breast Neoplasms
Human progesterone receptor displays cell cycle-dependent changes in transcriptional activity.
Breast Neoplasms
Identification of a promoter that controls aromatase expression in human breast cancer and adipose stromal cells.
Breast Neoplasms
Regulation by estrogen through the 5'-flanking region of the mouse calbindin-D28k gene.
Breast Neoplasms
Regulation by estrogen through the 5'-flanking region of the transforming growth factor alpha gene.
Breast Neoplasms
Restoration of aryl hydrocarbon (Ah) responsiveness in MDA-MB-231 human breast cancer cells by transient expression of the estrogen receptor.
Breast Neoplasms
Synergistic activation of estrogen receptor-mediated transcription by estradiol and protein kinase activators.
Breast Neoplasms
The human cytochrome Cyp1A2 gene contains regulatory elements responsive to 3-methylcholanthrene.
Breast Neoplasms
The progesterone antagonist RU486 acquires agonist activity upon stimulation of cAMP signaling pathways.
Breast Neoplasms
Two organochlorine pesticides, toxaphene and chlordane, are antagonists for estrogen-related receptor alpha-1 orphan receptor.
Bronchitis
cis-acting sequences required for coronavirus infectious bronchitis virus defective-RNA replication and packaging.
Bronchitis
Expression of reporter genes from the defective RNA CD-61 of the coronavirus infectious bronchitis virus.
Burkitt Lymphoma
Delineation of the cis-acting element mediating EBNA-2 transactivation of latent infection membrane protein expression.
Burkitt Lymphoma
Epstein-Barr virus nuclear antigen 2 transactivates latent membrane protein LMP1.
Carcinogenesis
Human immunodeficiency virus type 1 tat gene enhances human papillomavirus early gene expression.
Carcinogenesis
Trans-activation of glutathione transferase P gene during chemical hepatocarcinogenesis of the rat.
Carcinogenesis
[Regulation mechanism of specific expression of tumor marker gene during carcinogenesis]
Carcinoma
Cis-acting elements required for expression of the nonspecific cross-reacting antigen gene in colorectal carcinoma.
Carcinoma
Comparative functional analysis of the various lentivirus long terminal repeats in human colon carcinoma cell line (SW480 cells) and feline renal cell line (CRFK cells).
Carcinoma
Enhanced transcription of the human alpha 2A-adrenergic receptor gene by cAMP: evidence for multiple cAMP responsive sequences in the promoter region of this gene.
Carcinoma
Enhancer function of a 53-bp repetitive element in the 5' flanking region of the human neutrophil elastase gene.
Carcinoma
Evolutionary distinct mechanisms regulate apolipoprotein A-I gene expression: differences between avian and mammalian apoA-I gene transcription control regions.
Carcinoma
Extinction of the HPV18 upstream regulatory region in cervical carcinoma cells after fusion with non-tumorigenic human keratinocytes under non-selective conditions.
Carcinoma
Genomic cloning and characterization of the rat glutathione S-transferase-A3-subunit gene.
Carcinoma
Hepatocyte nuclear factor 3 is a major determinant of CYP2C6 promoter activity in hepatoma cells.
Carcinoma
Identification of multiple regulatory elements of human L-histidine decarboxylase gene.
Carcinoma
Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.
Carcinoma
The upstream region of the mouse N-myc gene: identification of an enhancer element that functions preferentially in neuroblastoma IMR32 cells.
Carcinoma
Transcriptional activation of stress genes and cytotoxicity in human liver carcinoma cells (HepG2) exposed to 2,4,6-trinitrotoluene, 2,4-dinitrotoluene, and 2,6-dinitrotoluene.
Carcinoma
Vincristine induction of mutant and wild-type human multidrug-resistance promoters is cell-type-specific and dose-dependent.
Carcinoma, Ductal
Prolactin acts on the extreme 5' portion of MMTV LTR involving a mammary cell-specific enhancer.
Carcinoma, Embryonal
Analysis of the binding proteins and activity of the long terminal repeat of Moloney murine leukemia virus during differentiation of mouse embryonal carcinoma cells.
Carcinoma, Embryonal
AP-1 and Krox-24 transcription factors activate the neurofilament light gene promoter in P19 embryonal carcinoma cells.
Carcinoma, Embryonal
De novo methylation of transfected CAT gene plasmid constructs in F9 mouse embryonal carcinoma cells.
Carcinoma, Embryonal
Enhancement of reporter gene de novo methylation by DNA fragments from the alpha-fetoprotein control region.
Carcinoma, Embryonal
Retinoic acid-dependent transactivation of major histocompatibility complex class I promoters by the nuclear hormone receptor H-2RIIBP in undifferentiated embryonal carcinoma cells.
Carcinoma, Embryonal
Transcriptional regulation of the int-2 gene in embryonal carcinoma cells.
Carcinoma, Hepatocellular
A distinct thyroid hormone response element mediates repression of the human cholesterol 7alpha-hydroxylase (CYP7A1) gene promoter.
Carcinoma, Hepatocellular
A hormone response element upstream from the human alcohol dehydrogenase gene ADH2 consists of three tandem glucocorticoid receptor binding sites.
Carcinoma, Hepatocellular
A liver-specific enhancer in the core promoter region of human hepatitis B virus.
Carcinoma, Hepatocellular
A possible mechanism of inverse developmental regulation of alpha-fetoprotein and albumin genes. Studies with epidermal growth factor and phorbol ester.
Carcinoma, Hepatocellular
A ubiquitous enhancer shared by two promoters in the human aldolase A gene.
Carcinoma, Hepatocellular
Activation of apolipoprotein AI gene expression by protein kinase A and kinase C through transcription factor, Sp1.
Carcinoma, Hepatocellular
Adenovirus E1A represses the cyclic AMP-induced transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) in hepatoma cells.
Carcinoma, Hepatocellular
Adenovirus enhancement of polyethylenimine-mediated transfer of regulated genes in differentiated cells.
Carcinoma, Hepatocellular
alpha-Naphthoflavone-induced CYP1A1 gene expression and cytosolic aryl hydrocarbon receptor transformation.
Carcinoma, Hepatocellular
Analysis of the transcriptional activity of the 5'-flanking region of the rat catalase gene in transiently transfected cells and in transgenic mice.
Carcinoma, Hepatocellular
ATF-like element contributes to hepatic activation of human angiotensinogen promoter.
Carcinoma, Hepatocellular
Beneficial effects of a novel thyromimetic on lipoprotein metabolism.
Carcinoma, Hepatocellular
Beta-adrenergic receptors and angiotensinogen gene expression in mouse hepatoma cells in vitro.
Carcinoma, Hepatocellular
Cell-specific enhancer activity in a far upstream region of the human alpha-fetoprotein gene.
Carcinoma, Hepatocellular
Cell-specific expression of mouse albumin promoter. Evidence for cell-specific DNA elements within the proximal promoter region and cis-acting DNA elements upstream of -160.
Carcinoma, Hepatocellular
Characterization of hamster CYP1A1 gene: inducible expression and negative regulation.
Carcinoma, Hepatocellular
Characterization of the chicken fatty acid synthase gene 5' part and promoter region.
Carcinoma, Hepatocellular
Characterization of the promoter region of the human MDR3 P-glycoprotein gene.
Carcinoma, Hepatocellular
cis-acting DNA elements regulating expression of the liver pyruvate kinase gene in hepatocytes and hepatoma cells. Evidence for tissue-specific activators and extinguisher.
Carcinoma, Hepatocellular
Cold-induced alterations in the binding of adrenomedullary nuclear proteins to the promoter region of the tyrosine hydroxylase gene.
Carcinoma, Hepatocellular
Constitutive and NF-kappa B-like proteins in the regulation of the serum amyloid A gene by interleukin 1.
Carcinoma, Hepatocellular
Constitutive expression of murine complement factor B gene is regulated by the interaction of its upstream promoter with hepatocyte nuclear factor 4.
Carcinoma, Hepatocellular
Evolutionary distinct mechanisms regulate apolipoprotein A-I gene expression: differences between avian and mammalian apoA-I gene transcription control regions.
Carcinoma, Hepatocellular
Expression of the chloramphenicol acetyltransferase (CAT) reporter gene by the murine Cyp1a-2 (cytochrome P3(450)) promoter in hepatoma cell cultures.
Carcinoma, Hepatocellular
Gene structure of mouse Cyp3a11: evidence for an enhancer element within its 5' flanking sequences.
Carcinoma, Hepatocellular
Genomic structure of and a cardiac promoter for the mouse carnitine palmitoyltransferase II gene.
Carcinoma, Hepatocellular
Glucocorticoid regulation of the rat cytochrome P450c (P450IA1) gene: receptor binding within intron I.
Carcinoma, Hepatocellular
Heavy metal-mediated activation of the rat Cu/Zn superoxide dismutase gene via a metal-responsive element.
Carcinoma, Hepatocellular
Hepatitis B virus X gene activates kappa B-like enhancer sequences in the long terminal repeat of human immunodeficiency virus 1.
Carcinoma, Hepatocellular
Hepatocyte nuclear factor 3 is a major determinant of CYP2C6 promoter activity in hepatoma cells.
Carcinoma, Hepatocellular
Hormonal discrimination among transcription start sites of aspartate aminotransferase.
Carcinoma, Hepatocellular
Human hepatitis B virus X protein is detectable in nuclei of transfected cells, and is active for transactivation.
Carcinoma, Hepatocellular
Human P45IA1 upstream regulatory sequences expressing the chloramphenicol acetyltransferase gene. Effect of Ha-MSV enhancer and comparison of transient with stable transformation assays.
Carcinoma, Hepatocellular
Identification and analysis of the gene encoding human PC2, a prohormone convertase expressed in neuroendocrine tissues.
Carcinoma, Hepatocellular
Identification of a promoter region for 3.6-kilobase mRNA of hepatitis B virus and specific cellular binding protein.
Carcinoma, Hepatocellular
Identification of cell type-dependent enhancer core element located in the 3'-downstream region of the human angiotensinogen gene.
Carcinoma, Hepatocellular
Identification of multiple regulatory elements on the human cytochrome P450IA1 gene.
Carcinoma, Hepatocellular
In vitro inhibition of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced activity by alpha-naphthoflavone and 6-methyl-1,3,8-trichlorodibenzofuran using an aryl hydrocarbon (Ah)-responsive construct.
Carcinoma, Hepatocellular
Inhibition by insulin of protein kinase A-induced transcription of the phosphoenolpyruvate carboxykinase gene. Mediation by the activation domain of cAMP response element-binding protein (CREB) and factors bound to the TATA box.
Carcinoma, Hepatocellular
Insulin stimulates glyceraldehyde-3-phosphate dehydrogenase gene expression through cis-acting DNA sequences.
Carcinoma, Hepatocellular
Interaction of interferon-alpha with interleukin-1 beta or tumor necrosis factor-alpha on hepatitis B virus enhancer activity.
Carcinoma, Hepatocellular
Introduction of the glucocorticoid binding sequences into the expression vector p delta SVE-CAT and its effect on the CAT gene expression in mammalian cells.
Carcinoma, Hepatocellular
Isolation and analysis of inducibility of the rat N-methylpurine-DNA glycosylase promoter.
Carcinoma, Hepatocellular
Location and characterization of multiple glucocorticoid-responsive elements in the rat serine dehydratase gene.
Carcinoma, Hepatocellular
Molecular cloning and analysis of the rat kallikrein-binding protein gene.
Carcinoma, Hepatocellular
Oligo-3-hydroxybutyrates as potential carriers for drug delivery.
Carcinoma, Hepatocellular
Organization of the 5' end of the rat gamma-glutamyl transpeptidase gene: structure of a promoter active in the kidney.
Carcinoma, Hepatocellular
Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE).
Carcinoma, Hepatocellular
Polymorphism in the human apolipoprotein A-I gene promoter region. Association of the minor allele with decreased production rate in vivo and promoter activity in vitro.
Carcinoma, Hepatocellular
Rat pyruvate kinase M gene. Its complete structure and characterization of the 5'-flanking region.
Carcinoma, Hepatocellular
Regulation of the human C-reactive protein gene, a major marker of inflammation and cancer.
Carcinoma, Hepatocellular
Regulation of the rat alpha-fetoprotein gene expression in liver. Both the promoter region and an enhancer element are liver-specific and negatively modulated by dexamethasone.
Carcinoma, Hepatocellular
S-adenosylmethionine decarboxylase gene expression in rat hepatoma cells: regulation by insulin and by inhibition of protein synthesis.
Carcinoma, Hepatocellular
Structural and functional analyses of the promoter of the murine multidrug resistance gene mdr3/mdr1a reveal a negative element containing the AP-1 binding site.
Carcinoma, Hepatocellular
Structural and functional analysis of the rat testis-specific histone H1t gene.
Carcinoma, Hepatocellular
Structure of the rainbow trout metallothionein B gene and characterization of its metal-responsive region.
Carcinoma, Hepatocellular
Suppression of the human erythropoietin gene expression by the TR2 orphan receptor, a member of the steroid receptor superfamily.
Carcinoma, Hepatocellular
The CCAAT/enhancer-binding protein trans-activates the human cholesteryl ester transfer protein gene promoter.
Carcinoma, Hepatocellular
The enhancer sequence of human hepatitis B virus can enhance the activity of its surface gene promoter.
Carcinoma, Hepatocellular
The hepatitis B virus core promoter is strongly activated by the liver nuclear receptor fetoprotein transcription factor or by ectopically expressed steroidogenic factor 1.
Carcinoma, Hepatocellular
The mechanism of the bidirectional regulation of the rat alpha-fetoprotein gene by glucocorticoid hormone.
Carcinoma, Hepatocellular
The rat albumin gene promoter is appropriately regulated in transient but not in stable transfections.
Carcinoma, Hepatocellular
The rat and human hemopexin genes contain an identical interleukin-6 response element that is not a target of CAAT enhancer-binding protein isoforms.
Carcinoma, Hepatocellular
The Y-box motif mediates redox-dependent transcriptional activation in mouse cells.
Carcinoma, Hepatocellular
Transcription regulation of rat glutathione S-transferase Ya subunit gene expression by chemopreventive agents.
Carcinoma, Hepatocellular
Transcriptional activation of Cu/Zn superoxide dismutase and catalase genes by panaxadiol ginsenosides extracted from Panax ginseng.
Carcinoma, Hepatocellular
Transcriptional regulation of alpha-fetoprotein expression by dexamethasone in human hepatoma cells.
Carcinoma, Hepatocellular
Transcriptional regulatory regions for expression of the rat pyruvate kinase M gene.
Carcinoma, Hepatocellular
Transfection of hepatic genes into adult rat hepatocytes in primary culture and their tissue-specific expression.
Carcinoma, Hepatocellular
Use of electroporation to introduce biologically active foreign genes into primary rat hepatocytes.
Carcinoma, Hepatocellular
Vanadate inhibits expression of the gene for phosphoenolpyruvate carboxykinase (GTP) in rat hepatoma cells.
Carcinoma, Hepatocellular
Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element.
Carcinoma, Squamous Cell
Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth.
Carcinosarcoma
[Cancer gene therapy by direct intratumoral injection: gene expression and intratumoral pharmacokinetics of plasmid DNA]
Choriocarcinoma
Cyclic AMP responsiveness of human gonadotropin-alpha gene transcription is directed by a repeated 18-base pair enhancer. Alpha-promoter receptivity to the enhancer confers cell-preferential expression.
Choriocarcinoma
Different levels of ovine interferon-tau gene expressions are regulated through the short promoter region including Ets-2 binding site.
Choriocarcinoma
DNA sequences involved in the transcriptional activation of a human placental lactogen gene.
Choriocarcinoma
Identification and characterization of cis-acting regulatory elements for the expression of the human aromatase cytochrome P-450 gene.
Choriocarcinoma
Identification and characterization of transcriptional regulatory elements of the human aromatase cytochrome P450 gene (CYP19).
Choriocarcinoma
Interleukin-6 stimulates placental lactogen expression by human trophoblast cells.
Choriocarcinoma
Molecular cloning and characterization of the cyclic AMP-responsive ovine CYP11A1 (cholesterol side-chain cleavage) gene promoter: DNase 1 protection of conserved consensus elements.
Choriocarcinoma
Progesterone regulates HLA-G gene expression through a novel progesterone response element.
Choriocarcinoma
Regulation of human placental lactogen expression by 1,25-dihydroxyvitamin D3.
Choriocarcinoma
Retinoic acid and thyroid hormone regulate placental lactogen expression in human trophoblast cells.
Choriocarcinoma
The upstream promoter of the human LDL receptor gene does not contain a cyclic AMP response element.
Choriocarcinoma
trans-acting factors interact with a cyclic AMP response element to modulate expression of the human gonadotropin alpha gene.
Choriocarcinoma
Transcriptional regulation of the human aromatase cytochrome P450 gene expression in human placental cells.
Classical Swine Fever
A recombinant classical swine fever virus stably expresses a marker gene.
Cockayne Syndrome
Transient expression of a plasmid gene, a tool to study DNA repair in human cells: defect of DNA repair in Cockayne syndrome; one thymine cyclobutane dimer is sufficient to block transcription.
Coinfection
In vivo and in vitro analysis of electrical activity-dependent expression of muscle acetylcholine receptor genes using adenovirus.
Coinfection
Molecular interactions of cytomegalovirus and the human and simian immunodeficiency viruses.
Colonic Neoplasms
Demonstration of promoter activity and alternative splicing in the region 5' to exon 1 of the APC gene.
Colorectal Neoplasms
Cis-acting elements required for expression of the nonspecific cross-reacting antigen gene in colorectal carcinoma.
Colorectal Neoplasms
Molecular cloning and structural characterization of the functional human thymosin beta4 gene.
Cystic Fibrosis
Characterization of the promoter region of the cystic fibrosis transmembrane conductance regulator gene.
Dental Plaque
Regulation of the gtfBC and ftf genes of Streptococcus mutans in biofilms in response to pH and carbohydrate.
Diphtheria
Pollen-specific expression of the Arabidopsis thaliana alpha 1-tubulin promoter assayed by beta-glucuronidase, chloramphenicol acetyltransferase and diphtheria toxin reporter genes.
Distemper
'Rescue' of mini-genomic constructs and viruses by combinations of morbillivirus N, P and L proteins.
Endometrial Neoplasms
Estrogen response module of the mouse lactoferrin gene contains overlapping chicken ovalbumin upstream promoter transcription factor and estrogen receptor-binding elements.
Endometrial Neoplasms
Involvement of mutations in the DPC4 promoter in endometrial carcinoma development.
Endometrial Neoplasms
Methoxychlor stimulates the mouse lactoferrin gene promoter through a GC-rich element.
Endometrial Neoplasms
Modulation of hepatocyte growth factor gene expression by estrogen in mouse ovary.
Endometrial Neoplasms
Promoter-specific activation of mouse lactoferrin gene by epidermal growth factor involves two adjacent regulatory elements.
Enzootic Bovine Leukosis
Activation of enhancer sequences in type II human T-cell leukemia virus and bovine leukemia virus long terminal repeats by virus-associated trans-acting regulatory factors.
Enzootic Bovine Leukosis
The bovine leukemia virus X region encodes a trans-activator of its long terminal repeat.
Equine Infectious Anemia
Localization of sequences responsible for trans-activation of the equine infectious anemia virus long terminal repeat.
Erythema
Evaluation of sunscreens with various sun protection factors in a new transgenic mouse model of cutaneous photoaging that measures elastin promoter activation.
Fibrosarcoma
Cooperative interaction of nuclear factor-kappa B- and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines.
Foot-and-Mouth Disease
Noncytopathic flavivirus replicon RNA-based system for expression and delivery of heterologous genes.
Foot-and-Mouth Disease
Replication-competent foot-and-mouth disease virus RNAs lacking capsid coding sequences.
Glioma
Analysis of the transcriptional activity of the 5'-flanking region of the rat catalase gene in transiently transfected cells and in transgenic mice.
Glioma
Cell type-specific regulation of CREB gene expression: mutational analysis of CREB promoter activity.
Glioma
Ethanol uses cAMP-independent signal transduction mechanisms to activate proenkephalin promoter activity in rat C6 glioma cells.
Glioma
Molecular cloning and characterization of the promoter region of the calcineurin A alpha gene.
Glioma
PKN interacts with a paraneoplastic cerebellar degeneration-associated antigen, which is a potential transcription factor.
Glioma
Sodium valproate inhibits production of TNF-alpha and IL-6 and activation of NF-kappaB.
Glioma
Tumor-selective gene transduction and cell killing with an oncotropic autonomous parvovirus-based vector.
Head and Neck Neoplasms
Direct involvement of the Y-box binding protein YB-1 in genotoxic stress-induced activation of the human multidrug resistance 1 gene.
Hepatitis
Influenza virus polymerase basic protein 1 interacts with influenza virus polymerase basic protein 2 at multiple sites.
Hepatitis
Mouse hepatitis virus nucleocapsid protein as a translational effector of viral mRNAs.
Hepatitis
Requirement of the 5'-end genomic sequence as an upstream cis-acting element for coronavirus subgenomic mRNA transcription.
Hepatitis
Using a defective-interfering RNA system to express the HE protein of mouse hepatitis virus for studying viral pathogenesis.
Hepatitis B
Defective and nondefective adenovirus vectors for expressing foreign genes in vitro and in vivo.
Hepatitis B
Hepatitis B virus (HBV) promoters are regulated by the HBV enhancer in a tissue-specific manner.
Hepatitis B
High expression of exogenous cDNAs directed by HIV-1 long terminal repeat in human cells constitutively producing HIV-1 tat and adenovirus E1A/E1B.
Hepatitis B
Identification of a promoter region for 3.6-kilobase mRNA of hepatitis B virus and specific cellular binding protein.
Hepatitis B
Identification of a region within the human immunodeficiency virus type 1 long terminal repeat that is essential for transactivation by the hepatitis B virus gene X.
Hepatitis B
Protein Kinase Activity of the Insulin Receptor Is Essential for Insulin-Regulated Gene Expression.
Hepatitis B
Trans-activation function of a 3' truncated X gene-cell fusion product from integrated hepatitis B virus DNA in chronic hepatitis tissues.
Hepatitis B
Trans-activation of the human immunodeficiency virus long terminal repeat by the hepatitis B virus X protein.
Hepatitis C
Noncytopathic flavivirus replicon RNA-based system for expression and delivery of heterologous genes.
Hepatitis, Chronic
Trans-activation function of a 3' truncated X gene-cell fusion product from integrated hepatitis B virus DNA in chronic hepatitis tissues.
Hepatoblastoma
A common functional polymorphism (C-->A substitution at position -863) in the promoter region of the tumour necrosis factor-alpha (TNF-alpha) gene associated with reduced circulating levels of TNF-alpha.
Hepatoblastoma
Coordinated induction of the c-jun gene with genes encoding quinone oxidoreductases in response to xenobiotics and antioxidants.
Hepatoblastoma
Identification of a human immunodeficiency virus type 1 TAR binding protein in human hepatoblastoma HepG2 cells that trans-activates HIV-1 LTR-directed gene expression.
Hepatoblastoma
Increase caused by interleukin-6 in promoter activity of guinea pig liver transglutaminase gene.
Hepatoblastoma
Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene.
Herpes Simplex
A bi-functional reporter plasmid for the simultaneous transient expression assay of two herpes simplex virus promoters.
Herpes Simplex
A modular system for the assay of transcription regulatory signals: the sequence TAATGARAT is required for herpes simplex virus immediate early gene activation.
Herpes Simplex
A single regulatory region modulates both cis activation and trans activation of the herpes simplex virus VP5 promoter in transient-expression assays in vivo.
Herpes Simplex
A tissue-specific transcriptional enhancer is found in the body of the HLA-DR alpha gene.
Herpes Simplex
A versatile method for the coupling of protein to DNA: synthesis of alpha 2-macroglobulin-DNA conjugates.
Herpes Simplex
Activation of gene expression by human herpesvirus 6 is reporter gene-dependent.
Herpes Simplex
Activation of human immunodeficiency virus by herpesvirus infection: identification of a region within the long terminal repeat that responds to a trans-acting factor encoded by herpes simplex virus 1.
Herpes Simplex
Activation of human papillomavirus type 18 gene expression by herpes simplex virus type 1 viral transactivators and a phorbol ester.
Herpes Simplex
Activation of immediate-early, early, and late promoters by temperature-sensitive and wild-type forms of herpes simplex virus type 1 protein ICP4.
Herpes Simplex
Activity of herpes simplex virus type 1 latency-associated transcript (LAT) promoter in neuron-derived cells: evidence for neuron specificity and for a large LAT transcript.
Herpes Simplex
An upstream enhancer regulating brown-fat-specific expression of the mitochondrial uncoupling protein gene.
Herpes Simplex
An upstream region of the rat luteinizing hormone beta gene binds estrogen receptor and confers estrogen responsiveness.
Herpes Simplex
BOX DNA: a novel regulatory element related to embryonal carcinoma cell differentiation.
Herpes Simplex
Comparison of upstream sequence requirements for positive and negative regulation of a herpes simplex virus immediate-early gene by three virus-encoded trans-acting factors.
Herpes Simplex
Differential activation of hybrid genes containing herpes simplex virus immediate-early or delayed-early promoters after superinfection of stable DNA-transfected cell lines.
Herpes Simplex
E1A control of gene expression is mediated by sequences 5' to the transcriptional starts of the early viral genes.
Herpes Simplex
Ecdysterone regulatory elements function as both transcriptional activators and repressors.
Herpes Simplex
Electric field-mediated gene transfer (electroporation) into mouse Friend and human K562 erythroleukemic cells.
Herpes Simplex
Estrogen and progesterone receptor-binding sites on the chicken vitellogenin II gene: synergism of steroid hormone action.
Herpes Simplex
Expression of recombinant genes containing herpes simplex virus delayed-early and immediate-early regulatory regions and trans activation by herpesvirus infection.
Herpes Simplex
Herpes simplex virus immediate-early promoters are responsive to virus and cell trans-acting factors.
Herpes Simplex
Herpes simplex virus trans-regulatory protein ICP27 stabilizes and binds to 3' ends of labile mRNA.
Herpes Simplex
Herpes simplex virus virion stimulatory protein mRNA leader contains sequence elements which increase both virus-induced transcription and mRNA stability.
Herpes Simplex
High efficiency transient expression of eukaryotic genes: use of an HSV-1 immediate early promoter (ICP4).
Herpes Simplex
Human immunodeficiency virus tat gene transfer to the murine central nervous system using a replication-defective herpes simplex virus vector stimulates transforming growth factor beta 1 gene expression.
Herpes Simplex
Human insulin gene expression in transgenic mice: mutational analysis of the regulatory region.
Herpes Simplex
Identification of a 6-base pair element involved in the sterol-mediated transcriptional regulation of farnesyl diphosphate synthase.
Herpes Simplex
Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells.
Herpes Simplex
Identification of a promoter mapping within the reiterated sequences that flank the herpes simplex virus type 1 UL region.
Herpes Simplex
Identification of an estrogen response element in the 3'-flanking region of the murine c-fos protooncogene.
Herpes Simplex
Identification of an estrogen-responsive element in the rat LH beta gene. DNA-estrogen receptor interactions and functional analysis.
Herpes Simplex
Identification of immediate-early-type cis-response elements in the promoter for the ribonucleotide reductase large subunit from herpes simplex virus type 2.
Herpes Simplex
Involvement of serum response element in okadaic acid-induced EGR-1 transcription in human T-cells.
Herpes Simplex
Liposome-mediated gene therapy using HSV-TK/ganciclovir under the control of human PSA promoter in prostate cancer cells.
Herpes Simplex
Mapping of interacting domains between the nucleocapsid protein and the phosphoprotein of vesicular stomatitis virus by using a two-hybrid system.
Herpes Simplex
Minimal transcriptional enhancer of simian virus 40 is a 74-base-pair sequence that has interacting domains.
Herpes Simplex
Molecular characterization of a novel transcription factor that controls stromelysin expression.
Herpes Simplex
Papillomavirus trans-activator protein E2 activates expression from the promoter for the ribonucleotide reductase large subunit from herpes simplex virus type 2.
Herpes Simplex
Regulation and cell-type-specific activity of a promoter located upstream of the latency-associated transcript of herpes simplex virus type 1.
Herpes Simplex
The chicken lysozyme 5' matrix attachment region increases transcription from a heterologous promoter in heterologous cells and dampens position effects on the expression of transfected genes.
Herpes Simplex
The Epstein-Barr virus (EBV) early promoter DR contains a cis-acting element responsive to the EBV transactivator EB1 and an enhancer with constitutive and inducible activities.
Herpes Simplex
The herpes simplex virus thymidine kinase gene promoter contains a novel thyroid hormone response element.
Herpes Simplex
The upstream regulatory region of the human papilloma virus-16 contains an E2 protein-independent enhancer which is specific for cervical carcinoma cells and regulated by glucocorticoid hormones.
Herpes Simplex
Three distinct nuclear protein binding sites in the promoter of the murine multidrug resistance mdr1b gene.
Herpes Simplex
Three trans-acting regulatory proteins of herpes simplex virus modulate immediate-early gene expression in a pathway involving positive and negative feedback regulation.
Herpes Simplex
trans activation of an Epstein-Barr viral transcriptional enhancer by the Epstein-Barr viral nuclear antigen 1.
Herpes Simplex
trans-activation and autoregulation of gene expression by the immediate-early region 2 gene products of human cytomegalovirus.
Herpes Simplex
Virus-induced modification of the host cell is required for expression of the bacterial chloramphenicol acetyltransferase gene controlled by a late herpes simplex virus promoter (VP5).
Hypersensitivity
Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells.
Infections
Activation of feline immunodeficiency virus long terminal repeat by feline herpesvirus type 1.
Infections
Activation of human immunodeficiency virus by herpesvirus infection: identification of a region within the long terminal repeat that responds to a trans-acting factor encoded by herpes simplex virus 1.
Infections
Baculovirus interaction with nontarget organisms: a virus-borne reporter gene is not expressed in two mammalian cell lines.
Infections
Cell-dependent requirement of human immunodeficiency virus type 1 Vif protein for maturation of virus particles.
Infections
Emergence of large plaque-producing clones of human immunodeficiency virus (HIV) in vitro.
Infections
Endothelial cell DNA transfer and expression using petri dish electroporation and the nonreplicating vaccinia virus/T7 RNA polymerase hybrid system.
Infections
Ex vivo monitoring of protein production in baculovirus-infected Trichoplusia ni larvae with a GFP-specific optical probe.
Infections
Expression of recombinant DNA introduced into Chlamydia trachomatis by electroporation.
Infections
General method for production and selection of infectious vaccinia virus recombinants expressing foreign genes.
Infections
Herpes simplex virus type 1 tegument protein VP22 is capable of modulating the transcription of viral TK and gC genes via interaction with viral ICP0.
Infections
Human immunodeficiency virus tat gene transfer to the murine central nervous system using a replication-defective herpes simplex virus vector stimulates transforming growth factor beta 1 gene expression.
Infections
Identification of upstream promoter elements mediating early transcription from the 35,000-molecular-weight protein gene of Autographa californica nuclear polyhedrosis virus.
Infections
Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation.
Infections
Inhibition of HIV-1 transcription by cyclopentenone prostaglandin A1 in Jurkat T lymphocytes.
Infections
Inhibition of interferon-inducible gene expression by adenovirus E1A proteins: block in transcriptional complex formation.
Infections
Interference to human immunodeficiency virus type 1 infection in the absence of downmodulation of the principal virus receptor, CD4.
Infections
Involvement of simian virus 40 (SV40) small t antigen in trans activation of SV40 early and late promoters.
Infections
NF-kappa B-binding proteins induced by HSV-1 infection of U937 cells are not involved in activation of human immunodeficiency virus.
Infections
Non-replicating vaccinia vector efficiently expresses bacteriophage T7 RNA polymerase.
Infections
Over-expression of ERT(ESX/ESE-1/ELF3), an ets-related transcription factor, induces endogenous TGF-beta type II receptor expression and restores the TGF-beta signaling pathway in Hs578t human breast cancer cells.
Infections
Persistent productive infection of human glial cells by human immunodeficiency virus (HIV) and by infectious molecular clones of HIV.
Infections
Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo.
Infections
Rapidly and slowly replicating human immunodeficiency virus type 1 isolates can be distinguished according to target-cell tropism in T-cell and monocyte cell lines.
Infections
Regulation of the herpesvirus saimiri (HVS) delayed-early 110-kilodalton promoter by HVS immediate-early gene products and a homolog of the Epstein-Barr virus R trans activator.
Infections
Repetitive adenovirus administration to the parotid gland: role of immunological barriers and induction of oral tolerance.
Infections
Restriction of vaccinia virus replication in CHO cells occurs at the stage of viral intermediate protein synthesis.
Infections
Retrovirus-mediated gene transfer into mouse cerebellar primary culture and its application to the neural transplantation.
Infections
Role of the DR2 repeat array in the regulation of the ICP34.5 gene promoter of herpes simplex virus type 1 during productive infection.
Infections
Segment-specific noncoding sequences of the influenza virus genome RNA are involved in the specific competition between defective interfering RNA and its progenitor RNA segment at the virion assembly step.
Infections
Substitution of murine transthyretin (prealbumin) regulatory sequences into the Moloney murine leukemia virus long terminal repeat yields infectious virus with altered biological properties.
Infections
The RR1 gene of herpes simplex virus type 1 is uniquely trans activated by ICP0 during infection.
Infections
Transactivating potential of the 3' open reading frame of murine mammary tumor virus.
Infections
Transduction of foreign regulatory sequences by a replication-defective herpes simplex virus type 1: the rat neuron-specific enolase promoter.
Infections
Vanadate inhibits expression of the gene for phosphoenolpyruvate carboxykinase (GTP) in rat hepatoma cells.
Infertility
Isolation of chloramphenicol acetyltransferase from soil bacteria for sterility testing of products containing chloramphenicol.
Influenza, Human
Amplification, expression, and packaging of foreign gene by influenza virus.
Influenza, Human
An influenza A virus containing influenza B virus 5' and 3' noncoding regions on the neuraminidase gene is attenuated in mice.
Influenza, Human
Efficient formation of influenza virus-like particles: dependence on the expression levels of viral proteins.
Influenza, Human
HOOK: a program for finding novel molecular architectures that satisfy the chemical and steric requirements of a macromolecule binding site.
Influenza, Human
In vivo analysis of the promoter structure of the influenza virus RNA genome using a transfection system with an engineered RNA.
Influenza, Human
Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation.
Influenza, Human
Influenza A virus NEP (NS2 protein) downregulates RNA synthesis of model template RNAs.
Influenza, Human
Influenza B viruses with site-specific mutations introduced into the HA gene.
Influenza, Human
Influenza virus naked RNA can be expressed upon transfection into cells co-expressing the three subunits of the polymerase and the nucleoprotein from simian virus 40 recombinant viruses.
Influenza, Human
Influenza virus polymerase basic protein 1 interacts with influenza virus polymerase basic protein 2 at multiple sites.
Influenza, Human
Inhibition of influenza virus RNA polymerase by 5'-capped short RNA fragments.
Influenza, Human
Intranasal inoculation of a recombinant influenza virus containing exogenous nucleotides in the NS segment induces mucosal immune response against the exogenous gene product in mice.
Influenza, Human
Mutational analysis of the influenza virus cRNA promoter and identification of nucleotides critical for replication.
Influenza, Human
Nucleotides in the panhandle structure of the influenza B virus virion RNA are involved in the specificity between influenza A and B viruses.
Influenza, Human
Rescue of a synthetic chloramphenicol acetyltransferase RNA into influenza virus-like particles obtained from recombinant plasmids.
Influenza, Human
Synthesis of biologically active influenza virus core proteins using a vaccinia virus-T7 RNA polymerase expression system.
Influenza, Human
The Cellular Factor NXP2/MORC3 Is a Positive Regulator of Influenza Virus Multiplication.
Influenza, Human
The polyadenylation signal of influenza virus RNA involves a stretch of uridines followed by the RNA duplex of the panhandle structure.
Influenza, Human
The replication activity of influenza virus polymerase is linked to the capacity of the PA subunit to induce proteolysis.
Influenza, Human
The RNA polymerase PB2 subunit is not required for replication of the influenza virus genome but is involved in capped mRNA synthesis.
Insulinoma
Human insulin gene expression in transgenic mice: mutational analysis of the regulatory region.
Insulinoma
Identification and analysis of the gene encoding human PC2, a prohormone convertase expressed in neuroendocrine tissues.
Insulinoma
Two 3',5'-cyclic-adenosine monophosphate response elements in the promoter region of the human gastric inhibitory polypeptide gene.
Latent Infection
Herpes simplex virus type 1 tegument protein VP22 is capable of modulating the transcription of viral TK and gC genes via interaction with viral ICP0.
Leukemia
Analysis of the binding proteins and activity of the long terminal repeat of Moloney murine leukemia virus during differentiation of mouse embryonal carcinoma cells.
Leukemia
c-myc intron element-binding proteins are required for 1, 25-dihydroxyvitamin D3 regulation of c-myc during HL-60 cell differentiation and the involvement of HOXB4.
Leukemia
Cell-specific expression of mouse albumin promoter. Evidence for cell-specific DNA elements within the proximal promoter region and cis-acting DNA elements upstream of -160.
Leukemia
Cloning and expression of the recombinant mouse natural killer cell granzyme Met-ase-1.
Leukemia
Comparison of various expression plasmids for the induction of immune response by DNA immunization.
Leukemia
Correlation of leukemogenic potential of murine retroviruses with transcriptional tissue preference of the viral long terminal repeats.
Leukemia
Functional analysis of a retroviral host-range mutant: altered long terminal repeat sequences allow expression in embryonal carcinoma cells.
Leukemia
Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance.
Leukemia
Human immunodeficiency virus type 1 vpr protein transactivation function: mechanism and identification of domains involved.
Leukemia
Identification of multiple regulatory elements of human L-histidine decarboxylase gene.
Leukemia
Involvement of a nuclear factor-kappa B-like protein in induction of the macrophage colony-stimulating factor gene by tumor necrosis factor.
Leukemia
Molecular characterization of the gene for human interleukin-1 beta converting enzyme (IL1BC).
Leukemia
Negative regulatory element associated with potentially functional promoter and enhancer elements in the long terminal repeats of endogenous murine leukemia virus-related proviral sequences.
Leukemia
Packaging of intron-containing genes into retrovirus vectors by alphavirus vectors.
Leukemia
Reconstitution of the functional granulocyte macrophage colony stimulating factor promoter: evidence for distinct activation mechanisms that mediate the response to phorbol ester/calcium and human T cell leukemia virus type I Tax signals.
Leukemia
Regulation of c-jun expression and AP-1 enhancer activity by granulocyte-macrophage colony-stimulating factor.
Leukemia
Transcription from a spleen necrosis virus 5' long terminal repeat is suppressed in mouse cells.
Leukemia
Transient gene expression by SV40 promoter characterizes sequential differentiation of embryonal carcinoma F9 cells into primitive and visceral endoderm.
Leukemia
Vanadate inhibits expression of the gene for phosphoenolpyruvate carboxykinase (GTP) in rat hepatoma cells.
Leukemia, Erythroblastic, Acute
Characterization of the Duffy gene promoter: evidence for tissue-specific abolishment of expression in Fy(a-b-) of black individuals.
Leukemia, Erythroblastic, Acute
Characterization of the promoter region of the human c-kit proto-oncogene.
Leukemia, Erythroblastic, Acute
Enhancer function of a 53-bp repetitive element in the 5' flanking region of the human neutrophil elastase gene.
Leukemia, Erythroblastic, Acute
Evidence for a globin promoter-specific silencer element located upstream of the human delta-globin gene.
Leukemia, Erythroblastic, Acute
Hereditary overexpression of adenosine deaminase in erythrocytes: studies in erythroid cell lines and transgenic mice.
Leukemia, Erythroblastic, Acute
Identification of a tumor necrosis factor-responsive element in the tumor necrosis factor alpha gene.
Leukemia, Erythroblastic, Acute
Short-term efficient expression of transfected DNA in human hematopoietic cells by electroporation: definition of parameters and use of chemical stimulators.
Leukemia, Erythroblastic, Acute
The palindromic series I repeats in the simian cytomegalovirus major immediate-early promoter behave as both strong basal enhancers and cyclic AMP response elements.
Leukemia, Erythroblastic, Acute
Transient expression of foreign genes in lymphoid cells is enhanced by phorbol ester.
Leukemia, Large Granular Lymphocytic
Cloning and expression of the recombinant mouse natural killer cell granzyme Met-ase-1.
Leukemia, Monocytic, Acute
Molecular characterization of the gene for human interleukin-1 beta converting enzyme (IL1BC).
Leukemia, Myeloid
Identification of transcriptional cis-elements in introns 7 and 9 of the myeloperoxidase gene.
Leukemia, Myeloid
Transcriptional regulation of the vimentin-encoding gene in mouse myeloid leukemia M1 cells.
Leukemia, T-Cell
A novel method for analysis of viral proteinase activity encoded by hepatitis C virus in cultured cells.
Leukemia, T-Cell
Reconstitution of the functional granulocyte macrophage colony stimulating factor promoter: evidence for distinct activation mechanisms that mediate the response to phorbol ester/calcium and human T cell leukemia virus type I Tax signals.
Leukemia, T-Cell
Transient gene expression by SV40 promoter characterizes sequential differentiation of embryonal carcinoma F9 cells into primitive and visceral endoderm.
Lymphoma
Localization of the inducible enhancer in the mouse interleukin-5 gene that is responsive to T-cell receptor stimulation.
Malaria
A new tool for the serodiagnosis of acute Plasmodium falciparum malaria in individuals with primary infection.
Marek Disease
Study on the structure of heteropolymer pp38/pp24 and its enhancement on the bi-directional promoter upstream of pp38 gene in Marek's disease virus.
Mastitis
Characterization of the chloramphenicol acetyltransferase variants encoded by the plasmids pSCS6 and pSCS7 from Staphylococcus aureus.
Measles
'Rescue' of mini-genomic constructs and viruses by combinations of morbillivirus N, P and L proteins.
Melanoma
17beta-estradiol, progesterone, and dihydrotestosterone suppress the growth of human melanoma by inhibiting interleukin-8 production.
Melanoma
Functional effects of a natural polymorphism in the transcriptional regulatory sequence of HLA-DQB1.
Melanoma
Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells.
Melanoma
Tumor-selective gene transduction and cell killing with an oncotropic autonomous parvovirus-based vector.
Metabolic Syndrome
Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells.
Neoplasm Metastasis
Endocervical involvement by endometrial carcinoma on fractional curettage: a clinicopathological study of 37 cases.
Neoplasms
11 beta-hydroxysteroid dehydrogenase activity in human lung cells and transcription regulation by glucocorticoids.
Neoplasms
11 beta-Hydroxysteroid dehydrogenase and tissue specificity of androgen action in human prostate cancer cell LNCaP.
Neoplasms
A frame-shift mutation in the androgen receptor gene causes complete androgen insensitivity in the testicular-feminized mouse.
Neoplasms
A microsphere-liposome (microplex) vector for targeted gene therapy of cancer. II. In vivo biodistribution study in a solid tumor model.
Neoplasms
A model for evaluating selective delivery of plasmid DNA to tumours via the vasculature.
Neoplasms
A single base mutation in the androgen receptor gene causes androgen insensitivity in the testicular feminized rat.
Neoplasms
A steroid-inducible promoter for the controlled overexpression of cloned genes in eukaryotic cells.
Neoplasms
A Y-box consensus sequence is required for basal expression of the human multidrug resistance (mdr1) gene.
Neoplasms
Activation of human multidrug resistance-1 gene promoter in response to heat shock stress.
Neoplasms
An element regulating adrenal-specific steroid 21-hydroxylase expression is located within the slp gene.
Neoplasms
Antiandrogens inhibit human androgen receptor-dependent gene transcription activation in the human prostate cancer cells LNCaP.
Neoplasms
Characterization and regulation of two testicular inhibin/activin beta B-subunit messenger ribonucleic acids that are transcribed from alternate initiation sites.
Neoplasms
Characterization of the promoter for the human long pentraxin PTX3. Role of NF-kappaB in tumor necrosis factor-alpha and interleukin-1beta regulation.
Neoplasms
Cloning of the genes for human stromelysin and stromelysin 2: differential expression in rheumatoid synovial fibroblasts.
Neoplasms
Constitutive AP-1 DNA binding and transactivating ability of malignant but not benign mouse epidermal cells.
Neoplasms
Decreased glucocorticoid receptor activity following glucocorticoid receptor antisense RNA gene fragment transfection.
Neoplasms
Differential expression of elafin in human normal mammary epithelial cells and carcinomas is regulated at the transcriptional level.
Neoplasms
Differential expression of the human gonadotropin alpha gene in ectopic and eutopic cells.
Neoplasms
Differential regulation of mouse mammary tumor virus-bacterial chloramphenicol acetyltransferase chimeric gene by human mineralocorticoid hormone-receptor complexes.
Neoplasms
Differential regulation of rat T-kininogen by tumor necrosis factor and interleukin-6.
Neoplasms
Effects of some new antiepileptic drugs and progabide on glucocorticoid receptor-mediated gene transcription in LMCAT cells.
Neoplasms
Endocervical involvement by endometrial carcinoma on fractional curettage: a clinicopathological study of 37 cases.
Neoplasms
Enhanced expression of the human multidrug resistance 1 gene in response to UV light irradiation.
Neoplasms
Expression and function of normal and LNCaP androgen receptors in androgen-insensitive human prostatic cancer cells. Altered hormone and antihormone specificity in gene transactivation.
Neoplasms
Expression of plant tumor-specific proteins in minicells of Escherichia coli: a fusion protein of lysopine dehydrogenase with chloramphenicol acetyltransferase.
Neoplasms
Extra mouse mammary tumor proviruses in DBA/2 mouse lymphomas acquire a selective advantage in lymphocytes by alteration in the U3 region of the long terminal repeat.
Neoplasms
Functional characterizations of the androgen receptor confirm that the molecular basis of androgen action is transcriptional regulation.
Neoplasms
Generation of therapeutic T-lymphocytes after in vivo tumor transfection with an allogeneic class I major histocompatibility complex gene.
Neoplasms
Human chromogranin A gene. Molecular cloning, structural analysis, and neuroendocrine cell-specific expression.
Neoplasms
Human progesterone receptor displays cell cycle-dependent changes in transcriptional activity.
Neoplasms
Identification and cell type specificity of the tyrosine hydroxylase gene promoter.
Neoplasms
Identification of a novel mammary cell line-specific enhancer element in the long terminal repeat of mouse mammary tumor virus, which interacts with its hormone-responsive element.
Neoplasms
Improvement of gene transfer to cervical cancer cell lines using non-viral agents.
Neoplasms
In vitro inhibition of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced activity by alpha-naphthoflavone and 6-methyl-1,3,8-trichlorodibenzofuran using an aryl hydrocarbon (Ah)-responsive construct.
Neoplasms
Inhibition of androgen action by dehydroepiandrosterone sulfotransferase transfected in PC-3 prostate cancer cells.
Neoplasms
Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response.
Neoplasms
Interaction of antiandrogen-androgen receptor complexes with DNA and transcription activation.
Neoplasms
Interleukin-6 induction by tumor necrosis factor and interleukin-1 in human fibroblasts involves activation of a nuclear factor binding to a kappa B-like sequence.
Neoplasms
Involvement of a DNA binding protein, MDR-NF1/YB-1, in human MDR1 gene expression by actinomycin D.
Neoplasms
Involvement of protein kinase in environmental stress-induced activation of human multidrug resistance 1 (MDR1) gene promoter.
Neoplasms
Isolation and characterization of the mouse P450 17 alpha-hydroxylase/C17-20-lyase gene (Cyp17): transcriptional regulation of the gene by cyclic adenosine 3',5'-monophosphate in MA-10 Leydig cells.
Neoplasms
Loss of androgen dependency with preservation of functional androgen receptors in androgen-dependent mouse tumor (Shionogi Carcinoma 115).
Neoplasms
Mutation of lysine 405 to serine in the parvovirus H-1 NS1 abolishes its functions for viral DNA replication, late promoter trans activation, and cytotoxicity.
Neoplasms
Negative control of the rat inhibin alpha subunit promoter in MA-10 Leydig tumour cells.
Neoplasms
p53 stimulates promoter activity of the sgk. serum/glucocorticoid-inducible serine/threonine protein kinase gene in rodent mammary epithelial cells.
Neoplasms
Partial androgen insensitivity caused by an androgen receptor mutation at amino acid 907 (Gly-->Arg) that results in decreased ligand binding affinity and reduced androgen receptor messenger ribonucleic acid levels.
Neoplasms
Phenylalanine-780 near the C-terminus of the mouse glucocorticoid receptor is important for ligand binding affinity and specificity.
Neoplasms
Prolactin acts on the extreme 5' portion of MMTV LTR involving a mammary cell-specific enhancer.
Neoplasms
Proteasome inhibitors reduce luciferase and beta-galactosidase activity in tissue culture cells.
Neoplasms
Regulation of androgen receptor gene expression by steroids and retinoic acid in human breast-cancer cells.
Neoplasms
Regulation of NF-kappaB and HIV-1 LTR activity in mouse L cells by ultraviolet radiation: LTR trans-activation in a nonirradiated genome in heterokaryons.
Neoplasms
Repression of cAMP-induced expression of the mouse P450 17 alpha-hydroxylase/C17-20 lyase gene (Cyp17) by androgens.
Neoplasms
Resistance to glucocorticoid-induced apoptosis in human T-cell acute lymphoblastic leukemia CEM-C1 cells is due to insufficient glucocorticoid receptor expression.
Neoplasms
Site-directed mutagenesis of the phosphorylation sites in the mouse glucocorticoid receptor.
Neoplasms
Specific region in hormone binding domain is essential for hormone binding and trans-activation by human androgen receptor.
Neoplasms
Stable transfection of androgen receptor and MMTV-CAT into mammalian cells: inhibition of cat expression by anti-androgens.
Neoplasms
Structural analysis and promoter characterization of the human collagenase-3 gene (MMP13).
Neoplasms
Structures of regulatory regions in the human cytochrome P-450scc (desmolase) gene.
Neoplasms
Targeted in vivo delivery of therapeutic gene into experimental squamous cell carcinomas using anti-epidermal growth factor receptor antibody: immunogene approach.
Neoplasms
The progesterone antagonist RU486 acquires agonist activity upon stimulation of cAMP signaling pathways.
Neoplasms
The simian virus 40 minimal origin and the 72-base-pair repeat are required simultaneously for efficient induction of late gene expression with large tumor antigen.
Neoplasms
The use of a DNA-binding domain replacement method for the detection of a potential TR3 orphan receptor response element in the mouse mammary tumor virus long terminal repeat.
Neoplasms
Transactivating potential of the 3' open reading frame of murine mammary tumor virus.
Neoplasms
Transcription factor decoy for nuclear factor-kappaB inhibits tumor necrosis factor-alpha-induced expression of interleukin-6 and intracellular adhesion molecule-1 in endothelial cells.
Neoplasms
Transcription of the Epstein-Barr virus gene EBNA-1 from different promoters in nasopharyngeal carcinoma and B-lymphoblastoid cells.
Neoplasms
Transcriptional activation and nuclear targeting signals of the human androgen receptor.
Neoplasms
Transcriptional activation by TR3 receptor, a member of the steroid receptor superfamily.
Neoplasms
Tumor necrosis factor-alpha inhibition of 17 alpha-hydroxylase/C17-20 lyase gene (Cyp17) expression.
Neoplasms
Use of the ornithine decarboxylase promoter to achieve N-MYC-mediated overexpression of a rabbit carboxylesterase to sensitize neuroblastoma cells to CPT-11.
Neurilemmoma
Binding at an NFI site is modulated by cyclic AMP-dependent activation of myelin basic protein gene expression.
Neuroblastoma
A 5'-flanking region of the bovine tyrosine hydroxylase gene is involved in cell-specific expression, activation of gene transcription by phorbol ester, and transactivation by c-Fos and c-Jun.
Neuroblastoma
Association of USF and c-Myc with a helix-loop-helix-consensus motif in the core promoter of the murine type II beta regulatory subunit gene of cyclic adenosine 3', 5'-monophosphate-dependent protein kinase.
Neuroblastoma
Autonomously replicating sequences identified in transcriptional regulatory regions of human N-myc gene.
Neuroblastoma
Characterization of the mouse dynamin I gene promoter and identification of sequences that direct expression in neuronal cells.
Neuroblastoma
Cold-induced alterations in the binding of adrenomedullary nuclear proteins to the promoter region of the tyrosine hydroxylase gene.
Neuroblastoma
Demonstration of an E-box and its CNS-related binding factors for transcriptional regulation of the mouse type 1 inositol 1,4,5-trisphosphate receptor gene.
Neuroblastoma
Expression of a chimeric VIP gene is targeted to the intestine in transgenic mice.
Neuroblastoma
Expression of the gene encoding human brain creatine kinase depends on sequences immediately following the transcription start point.
Neuroblastoma
Functional identification of the promoter for the gene encoding the alpha subunit of calcium/calmodulin-dependent protein kinase II.
Neuroblastoma
Identification of a retinoic acid response element in the human oxytocin promoter.
Neuroblastoma
Lineage-specific regulation of the vasoactive intestinal peptide gene in neuroblastoma cells is conferred by 5.2 kilobases of 5'-flanking sequence.
Neuroblastoma
Molecular cloning and characterization of the promoter region of the calcineurin A alpha gene.
Neuroblastoma
The 5'-flanking region of the synapsin I gene. A G+C-rich, TATA- and CAAT-less, phylogenetically conserved sequence with cell type-specific promoter function.
Neuroblastoma
The human synapsin II gene promoter. Possible role for the transcription factor zif268/egr-1, polyoma enhancer activator 3, and AP2.
Neuroblastoma
The mouse plasma membrane Ca2+ pump isoform 1 promoter: cloning and characterization.
Neuroblastoma
The upstream region of the mouse N-myc gene: identification of an enhancer element that functions preferentially in neuroblastoma IMR32 cells.
Neuroblastoma
Use of the ornithine decarboxylase promoter to achieve N-MYC-mediated overexpression of a rabbit carboxylesterase to sensitize neuroblastoma cells to CPT-11.
Newcastle Disease
High-level expression of a foreign gene from the most 3'-proximal locus of a recombinant Newcastle disease virus.
Obesity
Independent regulation of adipose tissue-specificity and obesity response of the adipsin promoter in transgenic mice.
Osteosarcoma
Characterization of the rat osteocalcin gene: stimulation of promoter activity by 1,25-dihydroxyvitamin D3.
Osteosarcoma
Expression of a provirus of human T cell leukaemia virus type I by DNA transfection.
Osteosarcoma
Expression of chloramphenicol acetyltransferase (CAT) from rodent type I collagen promoters in transfected osteosarcoma cells in vivo.
Osteosarcoma
Human herpesvirus 6A ts suppresses both transformation by H-ras and transcription by the H-ras and human immunodeficiency virus type 1 promoters.
Osteosarcoma
p53 transactivity during in vitro osteoblast differentiation in a rat osteosarcoma cell line.
Osteosarcoma
Regions of the rat osteocalcin gene which mediate the effect of 1,25-dihydroxyvitamin D3 on gene transcription.
Osteosarcoma
Structural and functional characterization of the human decorin gene promoter. A homopurine-homopyrimidine S1 nuclease-sensitive region is involved in transcriptional control.
Ovarian Neoplasms
Identification of tumor-specific paclitaxel (Taxol)-responsive regulatory elements in the interleukin-8 promoter.
Papilloma
Spironolactone, an aldosterone antagonist, acts as an antiglucocorticosteroid on the mouse mammary tumor virus promoter.
Papilloma
Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product.
Pheochromocytoma
Cold-induced alterations in the binding of adrenomedullary nuclear proteins to the promoter region of the tyrosine hydroxylase gene.
Pheochromocytoma
Glucocorticoids activate somatostatin gene transcription through co-operative interaction with the cyclic AMP signalling pathway.
Pheochromocytoma
Human chromogranin A gene. Molecular cloning, structural analysis, and neuroendocrine cell-specific expression.
Pheochromocytoma
Identification and cell type specificity of the tyrosine hydroxylase gene promoter.
Pheochromocytoma
Identification of a cyclic adenosine monophosphate-responsive element in the rat corticotropin-releasing hormone gene.
Pheochromocytoma
Promoter region of the rat phosphoribosylpyrophosphate synthetase-associated protein 39.
Pheochromocytoma
The human synapsin II gene promoter. Possible role for the transcription factor zif268/egr-1, polyoma enhancer activator 3, and AP2.
Pheochromocytoma
The promoter of the latency-associated transcripts of herpes simplex virus type 1 contains a functional cAMP-response element: role of the latency-associated transcripts and cAMP in reactivation of viral latency.
Pheochromocytoma
Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMP.
Pheochromocytoma
Upstream regions of the human cardiac actin gene that modulate its transcription in muscle cells: presence of an evolutionarily conserved repeated motif.
Pituitary Neoplasms
d(TG)n.d(CA)n sequences upstream of the rat prolactin gene form Z-DNA and inhibit gene transcription.
Pituitary Neoplasms
Distance-dependent interactions between basal, cyclic AMP, and thyroid hormone response elements in the rat growth hormone promoter.
Pituitary Neoplasms
Hormonal regulation of the bovine prolactin promoter in rat pituitary tumor cells.
Pituitary Neoplasms
Human chromogranin A gene. Molecular cloning, structural analysis, and neuroendocrine cell-specific expression.
Pituitary Neoplasms
Induction of human growth hormone promoter activity by the adenosine 3',5'-monophosphate pathway involves a novel responsive element.
Pituitary Neoplasms
Okadaic acid, a protein phosphatase inhibitor, enhances transcription of a receptor gene containing sequence A of the human prolactin promoter.
Plasmacytoma
NF-HB (BSAP) is a repressor of the murine immunoglobulin heavy-chain 3' alpha enhancer at early stages of B-cell differentiation.
Poliomyelitis
Retroviral vectors containing putative internal ribosome entry sites: development of a polycistronic gene transfer system and applications to human gene therapy.
Prostatic Neoplasms
Antiandrogens inhibit human androgen receptor-dependent gene transcription activation in the human prostate cancer cells LNCaP.
Prostatic Neoplasms
Expression of human prostatic acid phosphatase gene is regulated by upstream negative and positive elements.
Prostatic Neoplasms
Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells.
Prostatic Neoplasms, Castration-Resistant
Expression and function of normal and LNCaP androgen receptors in androgen-insensitive human prostatic cancer cells. Altered hormone and antihormone specificity in gene transactivation.
Rabies
Ambisense gene expression from recombinant rabies virus: random packaging of positive- and negative-strand ribonucleoprotein complexes into rabies virions.
Retinoblastoma
Endogenous CRX expression and IRBP promoter activity in retinoblastoma cells.
Rhabdomyosarcoma
Deletional analysis of the promoter region of the human transferrin receptor gene.
Rhabdomyosarcoma
Use of the ornithine decarboxylase promoter to achieve N-MYC-mediated overexpression of a rabbit carboxylesterase to sensitize neuroblastoma cells to CPT-11.
Rinderpest
'Rescue' of mini-genomic constructs and viruses by combinations of morbillivirus N, P and L proteins.
Sarcoma
Characterization of a 142-bp fragment of the murine c-fos oncogene promoter upstream of the SIF-binding element.
Sarcoma
Gene injection into canine myocardium as a useful model for studying gene expression in the heart of large mammals.
Sarcoma
Human P45IA1 upstream regulatory sequences expressing the chloramphenicol acetyltransferase gene. Effect of Ha-MSV enhancer and comparison of transient with stable transformation assays.
Sarcoma
Serum amyloid A gene expression under acute-phase conditions involves participation of inducible C/EBP-beta and C/EBP-delta and their activation by phosphorylation.
Sarcoma, Avian
Baculovirus-mediated expression of bacterial genes in dipteran and mammalian cells.
Sarcoma, Avian
Camptothecin inhibits Tat-mediated transactivation of type 1 human immunodeficiency virus.
Sarcoma, Avian
Characterization of the promoter for the alpha 1 (IV) collagen gene. DNA sequences within the first intron enhance transcription.
Sarcoma, Avian
Comparison of various expression plasmids for the induction of immune response by DNA immunization.
Sarcoma, Avian
Detection of transcription and translation in situ with biotinylated molecular probes in cells transfected with recombinant DNA plasmids.
Sarcoma, Avian
Effect of intercistronic length on internal ribosome entry site (IRES) efficiency in bicistronic mRNA.
Sarcoma, Avian
Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase.
Sarcoma, Avian
Expression of a prokaryotic gene in cultured lung endothelial cells after lipofection with a plasmid vector.
Sarcoma, Avian
Hormonal regulation of the bovine prolactin promoter in rat pituitary tumor cells.
Sarcoma, Avian
Human glucocorticoid receptor cDNA contains sequences sufficient for receptor down-regulation.
Sarcoma, Avian
Human immunodeficiency virus tat-activated expression of poliovirus protein 2A inhibits mRNA translation.
Sarcoma, Avian
Inhibition of transient gene expression with plasmids encoding herpes simplex virus type 1 UL55 and alpha genes.
Sarcoma, Avian
Insulin stimulates glyceraldehyde-3-phosphate dehydrogenase gene expression through cis-acting DNA sequences.
Sarcoma, Avian
Prenatal lethality in a transgenic mouse line is the result of a chromosomal translocation.
Sarcoma, Avian
The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos.
Sarcoma, Avian
The introduction of biologically active foreign genes into human respiratory epithelial cells using electroporation.
Sarcoma, Avian
The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.
Sarcoma, Avian
Tissue-specific expression in transgenic mice of a fused gene containing RSV terminal sequences.
Sarcoma, Avian
Transactivation of the Rous sarcoma virus long terminal repeat promoter by Marek's disease virus.
Severe Combined Immunodeficiency
Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth.
Starvation
Chloramphenicol induction of cat-86 requires ribosome stalling at a specific site in the leader.
Starvation
Drug-free induction of a chloramphenicol acetyltransferase gene in Bacillus subtilis by stalling ribosomes in a regulatory leader.
Starvation
Dual regulation of the ugp operon by phosphate and carbon starvation at two interspaced promoters.
Starvation
Induction of cat-86 by chloramphenicol and amino acid starvation in relaxed mutants of Bacillus subtilis.
Superinfection
A single regulatory region modulates both cis activation and trans activation of the herpes simplex virus VP5 promoter in transient-expression assays in vivo.
Superinfection
Differential activation of hybrid genes containing herpes simplex virus immediate-early or delayed-early promoters after superinfection of stable DNA-transfected cell lines.
Superinfection
Transactivation of the major capsid protein gene of herpes simplex virus type 1 requires a cellular transcription factor.
Teratocarcinoma
Negative and positive regulation by a short segment in the 5'-flanking region of the human cytomegalovirus major immediate-early gene.
Thymoma
A role for protein kinase C activity in interleukin-1 (IL-1) induction of IL-2 gene expression but not in IL-1 signal transduction.
Tuberculosis
Changed activation of HIV-1 LTR in monocytoid cells by mycobacteria with temporal progression of infection.
Tuberculosis
Mycobacterium tuberculosis enhances human immunodeficiency virus-1 replication by transcriptional activation at the long terminal repeat.
Tuberculosis
Phagocytosis of Mycobacterium tuberculosis modulates human immunodeficiency virus replication in human monocytic cells.
Tuberculosis
Risk Factors for Sputum Positive Pulmonary Tuberculosis Retreatment Cases and Factors Responsible for Treatment Outcome.
Tuberculosis
TNF-alpha-mediated activation of HIV-1 LTR in monocytoid cells by mycobacteria.
Tuberculosis, Pulmonary
Effect of green tea extract (catechins) in reducing oxidative stress seen in patients of pulmonary tuberculosis on DOTS Cat I regimen.
Urinary Bladder Neoplasms
Structural and functional analysis of the control region of the human DNA topoisomerase II alpha gene in drug-resistant cells.
Vaccinia
Activation of the human immunodeficiency virus type 1 long terminal repeat by vaccinia virus.
Vaccinia
An NH2-terminal peptide from the vaccinia virus L1R protein directs the myristylation and virion envelope localization of a heterologous fusion protein.
Vaccinia
Cell-free translation of a chimeric eucaryotic-procaryotic message yields functional chloramphenicol acetyltransferase.
Vaccinia
Determination of the promoter region of an early vaccinia virus gene encoding thymidine kinase.
Vaccinia
Determination of the transcriptional regulatory region of a vaccinia virus late gene.
Vaccinia
Eukaryotic transient expression system dependent on transcription factors and regulatory DNA sequences of vaccinia virus.
Vaccinia
General method for production and selection of infectious vaccinia virus recombinants expressing foreign genes.
Vaccinia
In vitro mutagenesis of the promoter region for a vaccinia virus gene: evidence for tandem early and late regulatory signals.
Vaccinia
Increased expression in vivo and in vitro of foreign genes directed by A-type inclusion body hybrid promoters in recombinant vaccinia viruses.
Vaccinia
Reduced steady-state levels of vaccinia virus-specific early mRNAs in interferon-treated chick embryo fibroblasts.
Vaccinia
Use of vaccinia virus vectors to study the synthesis, intracellular localization, and action of the human immunodeficiency virus trans-activator protein.
Vesicular Stomatitis
Noncytopathic flavivirus replicon RNA-based system for expression and delivery of heterologous genes.
Vesicular Stomatitis
The role of vesicular stomatitis virus matrix protein in inhibition of host-directed gene expression is genetically separable from its function in virus assembly.
Virus Diseases
Expression of phosphoenolpyruvate carboxykinase (PEPCK) chimeras in renal epithelial cells. Retention of appropriate physiological responsiveness using enhancerless retroviral vectors.
Virus Diseases
Multiple mechanisms are implicated in the regulation of NF-kappa B activity during human cytomegalovirus infection.
Virus Diseases
Multiple regulatory events influence human cytomegalovirus DNA polymerase (UL54) expression during viral infection.
Virus Diseases
Persistent productive infection of human glial cells by human immunodeficiency virus (HIV) and by infectious molecular clones of HIV.
Visna
Molecular mechanisms of visna virus Tat: identification of the targets for transcriptional activation and evidence for a post-transcriptional effect.
Visna
Nucleotide sequence and transcriptional activity of the caprine arthritis-encephalitis virus long terminal repeat.
Visna
The CAEV tat gene trans-activates the viral LTR and is necessary for efficient viral replication.
Visna
The visna virus long terminal repeat directs expression of a reporter gene in activated macrophages, lymphocytes, and the central nervous systems of transgenic mice.
Whooping Cough
The bvgA gene of Bordetella pertussis encodes a transcriptional activator required for coordinate regulation of several virulence genes.
Xeroderma Pigmentosum
Host cell reactivation by human cells of DNA expression vectors damaged by ultraviolet radiation or by acid-heat treatment.
Xeroderma Pigmentosum
Quantification of expression of linked cloned genes in a simian virus 40-transformed xeroderma pigmentosum cell line.
Xeroderma Pigmentosum
Transient expression of a plasmid gene, a tool to study DNA repair in human cells: defect of DNA repair in Cockayne syndrome; one thymine cyclobutane dimer is sufficient to block transcription.
html completed