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Information on EC 1.5.99.12 - cytokinin dehydrogenase

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IUBMB Comments
A flavoprotein (FAD). Catalyses the oxidation of cytokinins, a family of N6-substituted adenine derivatives that are plant hormones, where the substituent is a prenyl group. Although this activity was previously thought to be catalysed by a hydrogen-peroxide-forming oxidase, this enzyme does not require oxygen for activity and does not form hydrogen peroxide. 2,6-Dichloroindophenol, methylene blue, nitroblue tetrazolium, phenazine methosulfate and copper(II) in the presence of imidazole can act as acceptors. This enzyme plays a part in regulating rice-grain production, with lower levels of the enzyme resulting in enhanced grain production .
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
cytokinin oxidase, cytokinin oxidase/dehydrogenase, cytokinin dehydrogenase, osckx2, hvckx1, zmckx1, zmcko1, atckx2, atckx7, atckx3, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced acceptor
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