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arsenate + ?
arsenite + ?
-
-
-
-
?
arsenate + acetate
arsenite + ?
arsenate + benzyl viologen
arsenite + oxidized benzyl viologen
arsenate + methyl viologen
arsenite + oxidized methyl viologen
arsenate + reduced acceptor
arsenite + acceptor
arsenate + reduced dithiothreitol
arsenite + dithiothreitol
-
-
-
-
?
arsenate + reduced glutaredoxin
arsenite + acceptor
arsenite + acceptor
arsenate + reduced acceptor
arsenite + azurin + H2O
arsenate + reduced azurin
-
-
-
-
?
arsenite + cytochrome c + H2O
arsenate + reduced cytochrome c
-
-
-
-
?
arsenite + cytochrome c-551
arsenate + cytochrome c-551
arsenite + cytochrome c-551
arsenate + reduced cytochrome c-551
arsenite + oxidized 2,6-dichlorophenolindophenol
arsenate + reduced 2,6-dichlorophenolindophenol
sodium stibo(V)gluconate + reduced acceptor
sodium stibo(III)gluconate + acceptor
-
-
i.e. pentostam, reduction of antimony(V) to antimony(III)
-
?
additional information
?
-
arsenate + acetate
arsenite + ?
-
specific for arsenate
-
?
arsenate + acetate
arsenite + ?
-
anaerobic respiration using arsenate as terminal electron acceptor and acetate as the electron donor
-
?
arsenate + benzyl viologen
arsenite + oxidized benzyl viologen
-
-
-
-
r
arsenate + benzyl viologen
arsenite + oxidized benzyl viologen
-
-
-
-
r
arsenate + benzyl viologen
arsenite + oxidized benzyl viologen
-
-
-
-
r
arsenate + benzyl viologen
arsenite + oxidized benzyl viologen
-
-
-
-
r
arsenate + methyl viologen
arsenite + oxidized methyl viologen
-
-
-
-
r
arsenate + methyl viologen
arsenite + oxidized methyl viologen
-
-
-
-
r
arsenate + methyl viologen
arsenite + oxidized methyl viologen
-
-
-
-
r
arsenate + methyl viologen
arsenite + oxidized methyl viologen
-
-
-
-
r
arsenate + reduced acceptor
arsenite + acceptor
-
-
-
-
?
arsenate + reduced acceptor
arsenite + acceptor
-
-
-
-
?
arsenate + reduced acceptor
arsenite + acceptor
-
detoxification enzyme
-
-
?
arsenate + reduced acceptor
arsenite + acceptor
-
enzyme participates to achieve arsenate resistance to cells by reducing toxic arsenate to arsenite, arsenate is toxic due to its ability to mimic the phosphate group
-
-
?
arsenate + reduced acceptor
arsenite + acceptor
-
-
-
-
?
arsenate + reduced acceptor
arsenite + acceptor
-
detoxification enzyme, arsenite is excreted or sequestered
-
-
?
arsenate + reduced acceptor
arsenite + acceptor
-
detoxification enzyme, arsenite is extruded
-
-
?
arsenate + reduced acceptor
arsenite + acceptor
-
the chemical nature of As(III) product is determined by Arg60
-
-
?
arsenate + reduced acceptor
arsenite + acceptor
-
in the presence of glutathione, human glutaredoxin, and human glutathione reductase, Cdc25B is found to catalyze the reduction of As(V) to As(III)
-
-
?
arsenate + reduced acceptor
arsenite + acceptor
-
-
-
-
?
arsenate + reduced acceptor
arsenite + acceptor
-
in the presence of glutathione and with and without dithiothreitol, respectively. Glutathione and dithiothreitol in combination enhance arsenate reduction in vitro more than glutathione alone
-
-
?
arsenate + reduced glutaredoxin
arsenite + acceptor
yeast glutaredoxin ScGrx1p or Escherichia coli Grx2
-
-
?
arsenate + reduced glutaredoxin
arsenite + acceptor
-
yeast glutaredoxin ScGrx1p or Escherichia coli Grx2
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
detoxification of arsenite to the less toxic arsenate
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
detoxification of arsenite to the less toxic arsenate prior to methylation
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + cytochrome c-551
arsenate + cytochrome c-551
-
electron transport chain, overview
-
-
?
arsenite + cytochrome c-551
arsenate + cytochrome c-551
-
electron transport chain
-
-
?
arsenite + cytochrome c-551
arsenate + reduced cytochrome c-551
-
the bacterium obtains energy from the reaction, required for chemolithoautotrophic growth
-
-
?
arsenite + cytochrome c-551
arsenate + reduced cytochrome c-551
-
the bacterium obtains energy from the reaction, required for chemolithoautotrophic growth
-
-
?
arsenite + oxidized 2,6-dichlorophenolindophenol
arsenate + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
arsenite + oxidized 2,6-dichlorophenolindophenol
arsenate + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
arsenite + oxidized 2,6-dichlorophenolindophenol
arsenate + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
arsenite + oxidized 2,6-dichlorophenolindophenol
arsenate + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
additional information
?
-
-
enzyme acts both as arsenite oxidase and arsenate reductase
-
-
?
additional information
?
-
-
enzyme acts both as arsenite oxidase and arsenate reductase
-
-
?
additional information
?
-
-
the enzyme also catalyzes the tyrosine phosphatase reaction in vitro dephosphorylizing e.g. 4-nitrophenyl phosphate
-
-
?
additional information
?
-
-
the arsRDABC plasmid operon codes for an ATP-dependent anion pump and is responsible for resistance against arsenate, arsenite, antimonite, and tellurite
-
-
?
additional information
?
-
-
enzyme acts both as arsenite oxidase and arsenate reductase
-
-
?
additional information
?
-
-
enzyme acts both as arsenite oxidase and arsenate reductase
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
arsenate + acetate
arsenite + ?
-
anaerobic respiration using arsenate as terminal electron acceptor and acetate as the electron donor
-
?
arsenate + reduced acceptor
arsenite + acceptor
arsenite + acceptor
arsenate + reduced acceptor
arsenite + azurin + H2O
arsenate + reduced azurin
-
-
-
-
?
arsenite + cytochrome c + H2O
arsenate + reduced cytochrome c
-
-
-
-
?
arsenite + cytochrome c-551
arsenate + reduced cytochrome c-551
additional information
?
-
-
the arsRDABC plasmid operon codes for an ATP-dependent anion pump and is responsible for resistance against arsenate, arsenite, antimonite, and tellurite
-
-
?
arsenate + reduced acceptor
arsenite + acceptor
-
-
-
-
?
arsenate + reduced acceptor
arsenite + acceptor
-
detoxification enzyme
-
-
?
arsenate + reduced acceptor
arsenite + acceptor
-
enzyme participates to achieve arsenate resistance to cells by reducing toxic arsenate to arsenite, arsenate is toxic due to its ability to mimic the phosphate group
-
-
?
arsenate + reduced acceptor
arsenite + acceptor
-
detoxification enzyme, arsenite is excreted or sequestered
-
-
?
arsenate + reduced acceptor
arsenite + acceptor
-
detoxification enzyme, arsenite is extruded
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
detoxification of arsenite to the less toxic arsenate
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
detoxification of arsenite to the less toxic arsenate prior to methylation
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
-
-
-
-
?
arsenite + cytochrome c-551
arsenate + reduced cytochrome c-551
-
the bacterium obtains energy from the reaction, required for chemolithoautotrophic growth
-
-
?
arsenite + cytochrome c-551
arsenate + reduced cytochrome c-551
-
the bacterium obtains energy from the reaction, required for chemolithoautotrophic growth
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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Ellis, P.J.; Conrads, T.; Hille, R.; Kuhn, P.
Crystal structure of the 100 kDa arsenite oxidase from Alcaligenes faecalis in two crystal forms at 1.64 A and 2.03 A
Structure
9
125-132
2001
Alcaligenes faecalis
brenda
Krafft, T.; Macy, J.M.
Purification and characterization of the respiratory arsenate reductase of Chrysiogenes arsenatis
Eur. J. Biochem.
255
647-653
1998
Chrysiogenes arsenatis
brenda
Radabaugh, T.R.; Aposhian, H.V.
Enzymatic reduction of arsenic compounds in mammalian systems Reduction of arsenate to arsenite by human liver arsenate reductase
Chem. Res. Toxicol.
200; 13
26-30
2000
Homo sapiens
-
brenda
Guan, Z.; Hederstedt, L.; Li, J.P.; Su, X.D.
Preparation and crystallization of a Bacillus subtilis arsenate reductase
Acta Crystallogr. Sect. D
D57
1718-1721
2001
Bacillus subtilis
brenda
Hoke, K.R.; Cobb, N.; Armstrong, F.A.; Hille, R.
Electrochemical studies of arsenite oxidase: an unusual example of a highly cooperative two-electron molybdenum center
Biochemistry
43
1667-1674
2004
Alcaligenes faecalis
brenda
vanden Hoven, R.N.; Santini, J.M.
Arsenite oxidation by the heterotroph Hydrogenophaga sp. str. NT-14: the arsenite oxidase and its physiological electron acceptor
Biochim. Biophys. Acta
1656
148-155
2004
Hydrogenophaga sp. NT14, Hydrogenophaga sp. NT-26
brenda
Conrads, T.; Hemann, C.; George, G.N.; Pickering, I.J.; Prince, R.C.; Hille, R.
The active site of arsenite oxidase from Alcaligenes faecalis
J. Am. Chem. Soc.
124
11276-11277
2002
Alcaligenes faecalis
brenda
Bennett, M.S.; Guan, Z.; Laurberg, M.; Su, X.D.
Bacillus subtilis arsenate reductase is structurally and functionally similar to low molecular weight protein tyrosine phosphatases
Proc. Natl. Acad. Sci. USA
98
13577-13582
2001
Bacillus subtilis
brenda
DeMel, S.; Shi, J.; Martin, P.; Rosen, B.P.; Edwards, B.F.
Arginine 60 in the ArsC arsenate reductase of E. coli plasmid R773 determines the chemical nature of the bound As(III) product
Protein Sci.
13
2330-2340
2004
Escherichia coli
brenda
Martin, P.; DeMel, S.; Shi, J.; Gladysheva, T.; Gatti, D.L.; Rosen, B.P.; Edwards, B.F.P.
Insights into the structure, solvation, and mechanism of ArsC arsenate reductase, a novel arsenic detoxification enzyme
Structure
9
1071-1081
2001
Escherichia coli
brenda
Bisacchi, D.; Zhou, Y.; Rosen, B.P.; Mukhopadhyay, R.; Bordo, D.
Crystallization and preliminary crystallographic characterization of LmACR2, an arsenate/antimonate reductase from Leishmania major
Acta Crystallogr. Sect. F
F62
976-979
2006
Leishmania major
brenda
Guo, X.; Li, Y.; Peng, K.; Hu, Y.; Li, C.; Xia, B.; Jin, C.
Solution structures and backbone dynamics of arsenate reductase from Bacillus subtilis: reversible conformational switch associated with arsenate reduction
J. Biol. Chem.
280
39601-39608
2005
Bacillus subtilis
brenda
Li, Y.; Hu, Y.; Zhang, X.; Xu, H.; Lescop, E.; Xia, B.; Jin, C.
Conformational fluctuations coupled to the thiol-disulfide transfer between thioredoxin and arsenate reductase in Bacillus subtilis
J. Biol. Chem.
282
11078-11083
2007
Bacillus subtilis
brenda
Wang, L.; Meng, X.; Guo, B.; Duan, G.
Reduction of arsenic oxidative toxicity by phosphate is not related to arsenate reductase activity in wheat plants
J. Plant Nutr.
30
2105-2117
2007
Triticum sp.
-
brenda
Duan, G.L.; Zhou, Y.; Tong, Y.P.; Mukhopadhyay, R.; Rosen, B.P.; Zhu, Y.G.
A CDC25 homologue from rice functions as an arsenate reductase
New Phytol.
174
311-321
2007
Oryza sativa (Q10SX6), Oryza sativa (Q336V5)
brenda
Richey, C.; Chovanec, P.; Hoeft, S.E.; Oremland, R.S.; Basu, P.; Stolz, J.F.
Respiratory arsenate reductase as a bidirectional enzyme
Biochem. Biophys. Res. Commun.
382
298-302
2009
Shewanella sp., Alkalilimnicola ehrlichii, Alkaliphilus oremlandii, Shewanella sp. ANA-3
brenda
Srivastava, D.; Madamwar, D.; Subramanian, R.
Pentavalent arsenate reductase activity in cytosolic fractions of Pseudomonas sp., isolated from arsenic-contaminated sites of Tezpur, Assam
Appl. Biochem. Biotechnol.
162
766-779
2010
Pseudomonas sp.
brenda
Freikowski, D.; Winter, J.; Gallert, C.
Hydrogen formation by an arsenate-reducing Pseudomonas putida, isolated from arsenic-contaminated groundwater in West Bengal, India
Appl. Microbiol. Biotechnol.
88
1363-1371
2010
Pseudomonas putida
brenda
Bhattacharjee, H.; Sheng, J.; Ajees, A.; Mukhopadhyay, R.; Rosen, B.
Adventitious arsenate reductase activity of the catalytic domain of the human Cdc25B and Cdc25C phosphatases
Biochemistry
49
802-809
2010
Homo sapiens
brenda
Jareonmit, P.; Sajjaphan, K.; Sadowsky, M.J.
Structure and diversity of arsenic resistant bacteria in an old tin mine area of Thailand
J. Microbiol. Biotechnol.
20
169-178
2010
Betaproteobacteria, Arthrobacter koreensis
brenda
Nagarajan, V.; Ebbs, S.
Arsenate reductase activity in roots from the arsenic hyperaccumulator Pteris vittata utilizes both glutathione and dithiothreitol as reductants
Plant Biosyst.
144
857-859
2010
Pteris vittata
-
brenda
Mirza, B.S.; Sorensen, D.L.; Dupont, R.R.; McLean, J.E.
New arsenate reductase gene (arrA) PCR primers for diversity assessment and quantification in environmental samples
Appl. Environ. Microbiol.
83
e02725-16
2017
uncultured bacterium
brenda
Kumari, N.; Jagadevan, S.
Genetic identification of arsenate reductase and arsenite oxidase in redox transformations carried out by arsenic metabolising prokaryotes - A comprehensive review
Chemosphere
163
400-412
2016
Escherichia coli, Escherichia coli R773
brenda
Chaturvedi, N.; Pandey, P.N.
Phylogenetic analysis of gammaproteobacterial arsenate reductase proteins specific to Enterobacteriaceae family, signifying arsenic toxicity
Interdiscip. Sci.
6
57-62
2014
Acinetobacter sp., Enterobacter cloacae, Citrobacter sp., Escherichia coli, Hafnia alvei, Enterobacter sp., Klebsiella pneumoniae, Klebsiella sp., Salmonella sp., Serratia sp., Shigella flexneri, Shigella sp., Yersinia sp., Yokenella regensburgei
brenda
Sanchez-Bermejo, E.; Castrillo, G.; del Llano, B.; Navarro, C.; Zarco-Fernandez, S.; Martinez-Herrera, D.J.; Leo-del Puerto, Y.; Munoz, R.; Camara, C.; Paz-Ares, J.; Alonso-Blanco, C.; Leyva, A.
Natural variation in arsenate tolerance identifies an arsenate reductase in Arabidopsis thaliana
Nat. Commun.
5
4617
2014
Arabidopsis thaliana
brenda
Salt, D.
Would the real arsenate reductase please stand up?
New Phytol.
215
926-928
2017
Arabidopsis thaliana
brenda
Chao, D.Y.; Chen, Y.; Chen, J.; Shi, S.; Chen, Z.; Wang, C.; Danku, J.M.; Zhao, F.J.; Salt, D.E.
Genome-wide association mapping identifies a new arsenate reductase enzyme critical for limiting arsenic accumulation in plants
PLoS Biol.
12
e1002009
2014
Arabidopsis thaliana
brenda
Wu, D.; Tao, X.; Wu, G.; Li, X.; Liu, P.
Prokaryotic arsenate reductase enhances arsenate resistance in mammalian cells
Recent Pat. Food Nutr. Agric.
6
73-81
2014
Bacillus subtilis
brenda