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Information on EC 1.17.1.11 - formate dehydrogenase (NAD+, ferredoxin)

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EC Tree
IUBMB Comments
The enzyme complex, isolated from the bacterium Gottschalkia acidurici, couples the reduction of NAD+ and the reduction of ferredoxin with formate via flavin-based electron bifurcation.
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The expected taxonomic range for this enzyme is: Gottschalkia acidurici
Reaction Schemes
2
+
+
2
oxidized ferredoxin [iron-sulfur] cluster
=
2
+
+
+
2
reduced ferredoxin [iron-sulfur] cluster
Synonyms
EC 1.2.1.93, electron-bifurcating formate dehydrogenase, Fdh/Hyl, HylABC-FdhF2, NAD-dependent formate dehydrogenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 formate + NAD+ + 2 oxidized ferredoxin [iron-sulfur] cluster = 2 CO2 + NADH + H+ + 2 reduced ferredoxin [iron-sulfur] cluster
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