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Information on EC 1.14.99.48 - heme oxygenase (staphylobilin-producing)

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IUBMB Comments
This enzyme, which is found in some pathogenic bacteria, is involved in an iron acquisition system that catabolizes the host's hemoglobin. The two enzymes from the bacterium Staphylococcus aureus, encoded by the isdG and isdI genes, produce 67.5 % and 56.2 % delta-staphylobilin, respectively.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
heme oxidase, haem oxidase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
protoheme + 5 reduced acceptor + 4 O2 = beta-staphylobilin + Fe2+ + formaldehyde + 5 acceptor + 4 H2O
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protoheme + 5 reduced acceptor + 4 O2 = delta-staphylobilin + Fe2+ + formaldehyde + 5 acceptor + 4 H2O
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