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Information on EC 1.1.1.136 - UDP-N-acetylglucosamine 6-dehydrogenase

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IUBMB Comments
This enzyme participates in the biosynthetic pathway for UDP-alpha-D-ManNAc3NAcA (UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronic acid), an important precursor of B-band lipopolysaccharide.
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The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
udp-glcnac dehydrogenase, o180 o antigen, udp-n-acetylglucosamine 6-dehydrogenase, uglcnacdh, udp-glcnac 6-dehydrogenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-N-acetyl-alpha-D-glucosamine + 2 NAD+ + H2O = UDP-2-acetamido-2-deoxy-alpha-D-glucuronate + 2 NADH + 2 H+
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