3.4.21.B61: transmembrane protease serine 11D

This is an abbreviated version!
For detailed information about transmembrane protease serine 11D, go to the full flat file.

Reaction

The enzyme is involved in the proteolytic processing of angiotensin-converting enzyme 2 (ACE2) and of receptor PAR-2. It cleaves and activates the human coronavirus 229E (HCoV-229E) spike glycoprotein which facilitates virus-cell membrane fusions. =

Synonyms

HAT, human airway trypsin-like protease, MAT, TMPRSS11A, TMPRSS11D, TMPRSS1D, transmembrane protease serine 11A, transmembrane protease serine 11D

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.B61 transmembrane protease serine 11D

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Results	in table
2	AA Sequence
5	Application
6	Cloned(Commentary)
68	Disease/ Diagnostics
1	Expression
12	General Information
54	Inhibitors
3	kcat/KM [mM/s]
36	Ki Value [mM]
3	KM Value [mM]
3	Localization
2	Molecular Weight [Da]
22	Organism
1	pH Optimum
1	Posttranslational Modification
3	Protein Variants
1	Purification (Commentary)
1	Reaction
21	Reference
23	Source Tissue
1	Specific Activity [micromol/min/mg]
26	Substrates and Products (Substrate)
3	Subunits
13	Synonyms
3	Turnover Number [1/s]