3.1.4.12: sphingomyelin phosphodiesterase

This is an abbreviated version!
For detailed information about sphingomyelin phosphodiesterase, go to the full flat file.

Reaction

Synonyms

A-SMase, acid SMase, acid smase1, acid smase2, acid smase3, acid smase4, acid sphingomyelinase, acid sphingomyelinase-like phosphodiesterase 3B, acid spingomyelinase, acid-SMase, acidic SMase, acidic sphingomyelinase, alk-SMase, alkaline SMase, alkaline sphingomyelinase, alpha-toxin, ASM, aSMase, aSMase1, Bc-SMase, Beta-hemolysin, Beta-toxin, bSMase, ceramide-phosphocholine phosphodiesterase, ENPP7, haSMase, hnSMase, hSMase, intestinal alkaline sphingomyelinase, intestinal sphingomyelinase, Lyso-PAF-PLC, MA-nSMase, magnesium-dependent neutral sphingomyelinase, membrane associated neutral sphingomyelinase, Mg++-dependent sphingomyelinase, mitochondrial-associated neutral sphingomyelinase, mnSMase, More, N-mSMase, N-Sase, N-SMase, N-SMase2, neutral SMase, neutral SMase 1, neutral sphingomyelin-specific phospholipase C, neutral sphingomyelinase, neutral sphingomyelinase 1, neutral sphingomyelinase 2, neutral sphingomyelinase C, neutral sphingomyelinase-1, neutral sphingomyelinase-2, neutral sphingomyelinase-3, neutral sphingomyelinase-C, neutral sphingomylinase 2, NPP7, NSM, nSM1, nSM3, nSMase, nSMase 1, nSMase-1, NSMase-2, nSMase1, nSMase2, nSMase3, phosphodiesterase, sphingomyelin, phospholipase C/sphingomyelinase, PlcH, PlcHR2, PlcHR2 toxin, rhASM, S-mSMase, S-SMase, secretory sphingomyelinase, SKNY, SMase, SMase C, SMase I, SMase-C, SMC, SmcL, smdp3, SMPD, SMPD-1, SMPD1, smpd2, Smpd3, SMPD4, SMPDL3A, SMPDL3B, SMPLC, Sph2, sphingomyelin phosphodiesterase, sphingomyelin phosphodiesterase 1, sphingomyelin phosphodiesterase 3, sphingomyelin phosphodiesterase 5, sphingomyelin phosphodiesterase like 3a, sphingomyelin phosphodiesterase-1, sphingomyelinase, sphingomyelinase C, sphingomyelinase/hemolysin, Sphmase, T-mSMase

ECTree

     3 Hydrolases

         3.1 Acting on ester bonds

             3.1.4 Phosphoric-diester hydrolases

                3.1.4.12 sphingomyelin phosphodiesterase

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Results	in table
175	Activating Compound
4004	AA Sequence
14	Application
1	CAS Registry Number
82	Cloned(Commentary)
12	Crystallization (Commentary)
5690	Disease/ Diagnostics
10	Expression
76	General Information
7	General Stability
39	IC50 Value
362	Inhibitors
7	kcat/KM [mM/s]
2	Ki Value [mM]
56	KM Value [mM]
155	Localization
158	Metals/Ions
97	Molecular Weight [Da]
200	Natural Substrates/ Products (Substrates)
489	Organism
4	Pathway
49	PDB ID
113	pH Optimum
26	pH Range
3	pH Stability
4	pI Value
22	Posttranslational Modification
157	Protein Variants
76	Purification (Commentary)
11	Reaction
2	Reaction Type
263	Reference
1	Renatured (Commentary)
329	Source Tissue
68	Specific Activity [micromol/min/mg]
23	Storage Stability
428	Substrates and Products (Substrate)
61	Subunits
500	Synonyms
1	Systematic Name
39	Temperature Optimum [°C]
4	Temperature Range [°C]
17	Temperature Stability [°C]
10	Turnover Number [1/s]